Fourth seed Angelique Kerber won her first round match over Laura Robson in straight sets to record her first Grand Slam victory since defeating Serena Williams in Rod Laver Arena in the Australian Open final, as she was bundled out in the first round of the French Open losing to Kiki Bertens.
The German plays American Varvara Lepchenko in the second round, who has allegedly been tested positive for Meldonium which she refuses to comment on when asked about it in interviews.
Lepchenko has been ranked at a career high of 19 and the third round of Wimbledon back in 2012 has been the furthest she's been at the All England Club.
How they got here
Kerber played at the Aegon Classic in Birmingham as her only tune-up event heading into Wimbledon and her title defence was ended by Spaniard, Carla Suarez Navarro in the quarterfinals.
The German began her Wimbledon campaign against Britain's Laura Robson on No.1 court dispatching her in straight sets, gaining revenge for the loss she sustained to the Brit in the first round back in 2011.
Lepchenko came back from a set down to defeat clay courter Teliana Pereira in three sets, to set up this clash with the Australian Open champion.
Their history
Kerber and Lepchenko have played each other six times on the main WTA tour and the head-to-head is tied at three wins apiece.
The pair has played each other two times on hard courts and four times on clay, which means this second round match will be the first between the two on grass.
Lepchenko won their first three meetings dating back to 2007 at the Rogers Cup in the semifinals stage of qualifying winning 1-6, 6-0, 6-0, followed by a clay court victory in Ponte Vedra Beach and a win in the final round of qualifying for the Internazionali BNL d'Italia in 2011.
The German levelled their head-to-head by registering back-to-back French Open victories in 2013 and 2014 and on American soil in Stanford in 2014 on a hard court.
Their history at SW19
Kerber has lost in the third round of Wimbledon on three occasions in 2007, 2008 and 2011 and a second round exit in 2013.
The German reached the third round in 2010 and 2015 losing to fellow first-time slam winner Garbine Muguruza in the third round in 2015.
Kerber's run to the semifinals in 2012 was impressive as she was seeded eighth and recorded straight sets wins over Lucie Hradecka, Ekaterina Makarova, Christina McHale and Kim Clijsters to make her first Wimbledon quarterfinal.
In her first slam quarterfinal at SW19, Kerber defeated her compatriot and Fed Cup teammate Sabine Lisicki in three sets before losing to Agnieszka Radwanska in straight sets in the semifinals.
Kerber had a run to the quarterfinals in 2014, knocking out reigning French Open champion Maria Sharapova in straight sets in the fourth round but lost to Eugenie Bouchard in the quarterfinals for the second consecutive slam in a row after the Canadian knocked out Kerber in the fourth round of Roland Garros.
Lepchenko has only made the third round of Wimbledon once losing to the defending champion Petra Kvitova in 2012, picking up one game in the process.
Who wins?
The German lefty has tremendous movement on grass and she can retrieve balls from ridicolous positions.
Lepchenko is a lefty too and possesses a two-handed backhand which works nicely on the grass if she can excecute it.
Kerber's in the running to become world number one and if she does leave Wimbledon with the world number one ranking, it would be the pinnacle of her career along with winning the Australian Open.
This match is scheduled last on Court 12 on Day 3 of Wimbledon and the winner of this match will play Carina Witthoeft or Kurumi Nara in the third round.
Prediction: Kerber to win in straights