Holders Arsenal have been handed a home tie against Middlesbrough in the 5th Round of the FA Cup. Boro', who caused one of the major upsets of Round 4 after defeating Manchester City at the Etihad, will be in high spirits as they look to claim another Premier League scalp. 

Giant killers Bradford City will welcome either Fulham or Sunderland who will have to scrap it out again after contesting a 0-0 draw at the Stadium of Light on Saturday. Leicester City will travel to Villa Park in a tasty all Premier League Midlands derby to face Paul Lambert's side. Villa, who have reached the 5th Round for the first time in four years, will be hoping a cup run can spark some life into their shoddy league campaign. 

Preston North End or Sheffield United await Louis van Gaal's Manchester United, should they overcome Cambridge United at Old Trafford next week. Cambridge will travel North next Tuesday, after securing a replay against United on Friday, hoping they can provide one of the shocks of the season as they look to reach the 5th Round for the first time in 15 years.

New West Bromwich Albion boss Tony Pulis will get another chance to test his credentials against a Premier League side in the 5th Round as his side welcome a West Ham United side who will be looking to make a case for themselves in the competition after seeing the likes of Chelsea, Spurs & Manchester City crash out in Round 4. 

Alan Pardew's Crystal Palace await in the 5th Round for either Liverpool or Bolton Wanderers who also face a replay after their 0-0 stalemate at Anfield on Saturday. Meanwhile Derby County have been handed a home tie against Reading after their defeat of Chesterfield in the Derbyshire derby of Round 4. 

Mark Hughes will return to the side he first managed as he will take his Stoke City side to Ewood Park to face a Blackburn Rovers side who knocked out Premier League Swansea in the previous round.