Manchester United will kick-off the 2015/2016 campaign at home to Tottenham Hotspur on the weekend of 8/9 August.
United's first away game will be the following weekend (15th) at Aston Villa.
The first of derby fixtures against Liverpool will be September 19th at home with the away fixture on January 16th.
Manchester Derby part of a tough October
The Manchester derby will be on October 24th at Old Trafford, with the fixture at Manchester City being scheduled for March 19th.
October throws up three tricky away fixtures to Arsenal, Everton and Crystal Palace, as well as the home Manchester derby.
Boxing day sees United travel to the Brittania Stadium to face Stoke City and the Reds will wrap up the season at home to AFC Bournemouth on May 15th.
Full fixture list below:
Sat Aug 8 Tottenham Hotspur H
Sat Aug 15 Aston Villa A
Sat Aug 22 Newcastle United H
Sat Aug 29 Swansea City A
Sat Sep 12 Liverpool H
Sat Sep 19 Southampton A
Sat Sep 26 Sunderland H
Sat Oct 3 Arsenal A
Sat Oct 17 Everton A
Sat Oct 24 Manchester City H
Sat Oct 31 Crystal Palace A
Sat Nov 7 West Bromwich Albion H
Sat Nov 21 Watford A
Sat Nov 28 Leicester City A
Sat Dec 5 West Ham United H
Sat Dec 12 A.F.C. Bournemouth A
Sat Dec 19 Norwich City H
Sat Dec 26 Stoke City A
Mon Dec 28 Chelsea H
Sat Jan 2 Swansea City H
Wed Jan 13 Newcastle United A
Sat Jan 16 Liverpool A
Sat Jan 23 Southampton H
Tue Feb 2 Stoke City H
Sat Feb 6 Chelsea A
Sat Feb 13 Sunderland A
Sat Feb 27 Arsenal H
Tue Mar 1 Watford H
Sat Mar 5 West Bromwich Albion A
Sat Mar 12 Crystal Palace H
Sat Mar 19 Manchester City A
Sat Apr 2 Everton H
Sat Apr 9 Tottenham Hotspur A
Sat Apr 16 Aston Villa H
Sat Apr 23 West Ham United A
Sat Apr 30 Leicester City H
Sat May 7 Norwich City A
Sun May 15 A.F.C. Bournemouth H
All dates are subject to change, due to television coverage and European fixtures.