The Wolves have an emphatic 4-0 advantage from the first leg, where they raced into a three goal lead before half time. Isabel Kerschowski, Alexandra Popp and Babett Peter put them into a dominant position by the interval, while Ramona Bachmann added one for good measure before the hour.
Frankfurt winning 4-0 or 5-0 at home in a general fixture isn't difficult to imagine, but it is against a team of Wolfsburg's quality.
Playing for pride
The hosts may not be willing to admit defeat in this tie just yet - and to be fair to them, they aren't facing the 7-0 deficit that Paris Saint-Germain are in their semi-final with Olympique Lyonnais - but their chances of progressing are still very slim.
The last time Wolfsburg conceded four goals in a game was all the way back in 2010, losing 4-0 to 1. FFC Turbine Potsdam. Frankfurt put five past them that same season, but even that was only a win by a four-goal cushion in a 5-1 result. A 4-0 result tomorrow would take us to extra time, and 5-1 would see Wolfsburg progress on away goals.
The last time the Wolves lost by a scoreline that would see Frankfurt progress to the final tomorrow was in 2008; when they 9-1 to MSV Duisburg. Duisburg are now in the 2. Frauen-Bundesliga, which says everything one needs to know about how long ago that was and how much has changed since.
Frankfurt must be record-breakers to beat record-equallers
The first leg result in this tie was a record-equalling one. 4-0 is the heaviest defeat suffered by the competition's reigning champion, matching the score that Frankfurt themselves beat Potsdam by in 2006 when the latter were holders.
For Frankfurt to overturn this deficit, they would have to go one better and become record-breakers.
Wolfsburg have an unbeaten record away from home in Europe, and have not lost any of their 16 games on the road in this competition. FFC would have to snap this incredible streak to make the final and deny the Wolves a shot at their third European success in four seasons.
These two haven't played since they met in the first leg, so there's been plenty of time for players to recover for the clash and fatigue should not come as a problem either.
The Wolves are after their 10th successive win in all competitions, and to extend a 13-match unbeaten run. They have no fresh injury concerns to hinder them, but are still without sidelined trio Caroline Graham Hansen, Julia Simic and Noelle Maritz.
Frankfurt, on the other hand, are looking to avoid a third consecutive defeat after falling to SC Freiburg prior to defeat in the first leg of this tie.
They will hope to have Kerstin Garefrekes fully fit after she was only able to feature from the bench last time out, and will hope Dzsenifer Marozsan is feeling back to her best after completing 90 minutes in that game, despite being an injury doubt before it.
They have no other concerns when it comes to injuries though, and will hope their fully fit squad can complete an incredible comeback in tomorrow's second leg.