The maverick striker, 32, picked up a heel injury in a Ligue 1 fixture, so will not be fit for the return of his former club, whom he left to make the switch to Paris in 2012.
The French outfit could only draw with Ajax in the first round of fixtures, with Edinson Cavani opening the scoring early on, but a late Lasse Schone costless-kick ensured that the Laurent Blanc's side left the Netherlands having dropped two points.
Barcelona scraped through their first fixture, just pipping underdogs Apoel Nicosia 1-0, thanks to a Gerard Pique header. The Cypriots surprised everyone with their surprisingly resilient defence and will be hoping to go a step further when they take on Ajax tomorrow night.
Barcelona are top of La Liga, after a phenomenal start to the season, winning five out of their six games while scoring 17 and only conceding one. Neymar and Lionel Messi are beginning to build a formidable partnership and they will have a third 'amigo' in October when new signing Luis Suarez completes his ban.
The Catalan's opponents and tomorrow's hosts, Paris Saint-Germain have made a fairly under-par start, drawing five games out of their first eight, putting the Champions in a disappointing fourth-place.