Wolfsburg travel to the Commerzbank-Arena on Tuesday hoping to make it three wins in a row in the Bundesliga.
The Wolves go in to the game on the back of an astonishing 4-1 win over leaders Bayern Munich on Saturday.
Two goals from Bas Dost and two from Kevin De Bruyne cut the gap to eight points between them and Munich.
A win at Frankfurt could see them cut the gap to five points should Munich lose to Schalke. Should they avoid defeat, it'll be seven games unbeaten for them, which is the kind of form that they will need to keep them in touching distance of Munich.
The Wolves' new signing Andre Schürrle could make his debut after signing from Chelsea on deadline day.
The hosts will be keen to bounce back from Saturday's heavy 4-1 defeat to SC Freiburg.
Manager Thomas Schaaf will be expecting a good response from his side after that surprise result. Schaaf may look to change the side a little, but it's likely he'll stick with the same side that's done well so far this season.
The Eagles will be hoping strikers Alexander Meier and Haris Seferovic will be back on top form after Saturday's defeat.
Predicted line-ups:
Frankfurt: Trapp - Kinsombi, Zambrano, Anderson, Oczipka - Stendera, Hasebe - Aigner, Inui - Seferovic, Meier
Wolfsburg: Benaglio - Vieirinha, Naldo, Knoche, Rodriguez - Arnold, Luiz Gustavo - D. Caligiuri, De Bruyne, Perisic - Dost