Following the opening weekend of fixtures, only England and France are capable of winning the Grand Slam this season. England picked up a hard-fought win at Murrayfield against Scotland, whilst France fought back to narrowly see off Italy in Paris.
On Sunday, the game of the weekend saw Wales draw 16-16 with hosts Ireland in a game both teams will feel they should have won. Every team in the competition, barring Scotland, will have taken positives from their first matches as they look ahead to week two of the competition.
This weekend opens up with France hosting the Irish, which is followed by Wales versus Scotland in Saturday's double header. The only game on Sunday, sees current leaders England travel to Rome to take on the Italians.
France - Ireland
Despite beating Italy in his first game in charge, French boss Guy Noves has changed a large portion of his team, making six changes to the starting lineup. It was anything but a complete performance last weekend, and they only just snuck home so improvement will be needed against the Irish. Virimi Vakatawa retains his place on the left wing following his starring role on his debut last Saturday.
Teddy Thomas comes in on the right wing, whilst Maxime Mermoz takes over from Gael Fickou in the centres. In the pack, Yacouba Camara starts in the back row in place of the injured Louis Picamoles, whilst Alexandre Flanquart relegates Paul Jedrasiak to the bench in the second row. Noves has also changed his two starting props, with Jefferson Poirot and Uini Atonio coming in for Rabah Slimani and Eddy Ben Arous who drop to the bench.
The visitors, meanwhile have made three changes to their starting lineup as they go in search of their first win of the competition. Leinster pair Rob Kearney and Sean O'Brien have overcome knocks to return to the lineup. The third change sees Rob's brother, Dave Kearney, take Keith Earls place on the wing. Johnny Sexton and Andrew Trimble have overcome knocks to maintain their places in the side.
Wales - Scotland
Welsh fly-half, Dan Biggar has made a 'miraculous recovery' and will start on Saturday against the Scots. After leaving the field early in the game last week with an ankle injury, Biggar has recovered in time and has been named in an unchanged starting lineup.
On the bench, utility back Gareth Anscombe takes Alex Cuthbert's spot in the 23, with Warren Gatland again choosing to go with a flanker pairing of Sam Warburton and Justin Tipuric, with Dan Lydiate remaining on the bench.
After a desperately disappointing start last week, Scotland have only made one change to their matchday squad, with Duncan Taylor taking over from the injured Matt Scott in the inside centre position. Taylor has been in fine form for Saracens this campaign and his partnership with Mark Bennett will be crucial to any chance Scotland have of beating Wales at the Millennium Stadium.
Italy - England
After nearly beating the French, Italy's head coach Jacques Brunel has only made one change to his side ahead of their first home match of the tournament. Full-back David Odiete has pulled out with a neck injury, with his spot in the team being taken by Luke McLean. There are also two changes on the bench, with Edoardo Padovani and potential Test debutant Abraham Steyn coming into the matchday 23.
Eddie Jones has made three changes in his second England selection, in a game in which he will be hoping his side lay down a marker ahead of tougher tests in the competition. Ben Youngs swaps places with Danny Care who drops to the bench, while elsewhere Mako Vunipola and Courtney Lawes come in for Joe Marler and Joe Launchbury.
The bench sees two potential debutants in Maro Itoje and Paul Hill, where Jones has decided for a 6-2 split in favour of the forwards. The bench is full of youthful players who will look to run the Italians into the ground in the final quarter of the match and to make it two wins from two.