Alex Hales, Eoin Morgan and Joe Root were all missing for differing reasons, while Mark Wood's injury ruled him out on the eve of series.
The 2-1 win came thanks to a brilliant figthback in game one, with a thrilling victory in the decider coming after a poor defeat in the second game. There were ups and downs, with some players laying down a marker ahead of a busy year of one-day cricket, culminating in the Champions Trophy on home soil next summer.
Duckett makes his mark, while Stokes stands up to grab Player of the Series
Jason Roy 6/10 - Started the series with a solid 41 to lead England's total of 309, before only making 13 as England collapsed in the second game. Missed the decider through injury, but is definitely a big part of England's white-ball cricket.
James Vince 4/10 - Unfortunately for Vince, scores of 16, 5 and 32 just aren't going to cut it, and he looks set for a period of time back in county cricket before being able to stake a claim to return to the international arena.
Ben Duckett 8/10 - Lived up to the hype on debut, making 60 as he shared in a match-winning partnership with Ben Stokes, before firing 63 in Chittagong as England chased down 278 to claim the series.
Jonny Bairstow 6/10 - With limited chances in one-day cricket, Bairstow's return of 50 runs over three innings probably won't be enough to guarantee him a starting place if everybody is fit and firing.
Ben Stokes 9/10 - Man of the series, Stokes started with a tremendous 101 in Dhaka to notch his first ODI century, before making an unbeaten 47 to take England home in the decider. Chipped in with two wickets at a low economy rate, while players have spoken of the strong leadership he has offered on this tour.
Jos Buttler 8/10 - Making 63, 57 and 25, Buttler could not have done much more, captaining the side excellently in Morgan's absence.
Rashid and Ball the pick of the bowlers
Moeen Ali 2/10 - Hitting 11 runs and capturing just one wicket over three matches is not good enough for one of the team's premier all-rounders whatever the situation, and improvements are needed going forward.
Chris Woakes 4/10 - Pitches didn't suit his bowling style, and it showed with the Warwickshire man taking just two wickets at the cost of 134 runs from his 24 overs. He did however play a vitally important role in winning the series, making 27 not out from 18 balls to take the side home in Chittagong.
David Willey 3/10 - Dropped by the time the third match came around, Willey failed to register a wicket from his 15 overs.
Adil Rashid 9/10 - A vital cog in England's bowling attack, Rashid's ten wickets from the three matches are equal with the record for any spin bowler in a series of this length. His 4/49 helped alter the result in the opener when England looked set for defeat, with his 4/43 in the final match helping restrict the home side to 277.
Jake Ball 8/10 - Ball's 5/51 on debut were the best ever for an England bowler, and the scenes of him dripping with sweat yet bowling his full allotment of overs with aplomb will stay in the mind of his coaches going forward.
Billings impresses in final ODI at top of the order
Sam Billings 7/10 - Utilised as an opener in the decider due to Roy's injury, Billings took his chance magnificently with a vital 62. Highly rated by coaches and the media, England need to find a place for the talented youngster in their side.
Liam Plunkett 3/10 - Only selected for the last game due to injury, Plukett was hit for 51 from his nine overs.