Similarly, travelling side Luton won their first league match 0-1 against Barnsley at Oakwell, and so will also be looking to maintain their 100% record this season.
If the two sides needed any extra motivation, the winner of this fixture will host giants Manchester United in the third round next week.
Both sides have started the new season on fine form, and that is mainly down to the goal-scoring exploits of two men.
For the Berkshire-based side it is Portuguese striker Lucas Joao.
Signed last year for a reported £5 million, the former Sheffield Wednesday forward averaged a goal contribution every other game, although it was an injury-hit year and he only played 20 league matches.
This season he has five goal contributions in two matches, including a hattrick against Colchester United in the opening round of this competition.
If they can keep him fit and firing, they have a strong forward line to choose from with Yakou Meite and George Puscas also in the squad.
The visitors meanwhile have their own scoring machine, Irish international James Collins.
He also has four goals to his name, including a first round Carabao Cup hattrick against Norwich City.
With clean sheets in both of the sides' league matches last weekend, it could be down to the quality of striker to separate the two.
The last two these sides met was in July as Mark Bowen's Reading ran riot at Kenilworth Road, beating Nathan Jones' side 0-5.
A four-goal haul for Meite and a fifth from Puscas sealed the sides biggest score-line of the season.
Reading did the doubled over Luton last season having also beaten them 3-0 at the Madejski in November.
With it being a League Cup fixture, changes are expected from both sides.
Ivorian Meite has served the final game of this three-match ban and so is in contention for his first competitive action of the season.
Puscas and young defender Tom McIntyre are both back from international duty with Romania and Scotland Under-23s respectively, and so are also in contention.
Welshman Jones has nothing but admiration for Reading and expects a tough game in Berkshire.
"Reading are quite innovative with a lot of their managers, they don’t go for the obvious choice and they have had good success with that, especially Jaap Stam.
“Ironically it was my first taste of managerial action. I was caretaker manager at Brighton, against Steve Clarke and we ended up drawing 2-2, two-nil down after 11 minutes so it wasn’t the best start. We rallied, equalised late on and probably should have won the game.
"We got promoted ahead of them when I was at Brighton, Steve Coppell left to go to them so they’re a good side. Recently a Premier League side, wonderful players, so it’s going to be a real tough game but these are the teams you want to test yourself against, magnificent prize awaiting for the winner so a bit of added spice.”
How to Watch
The game is available on both club's iFollow services for £10.
Highlights will be available on 'Carabao Cup On Quest' tomorrow at 22.20 BST.