Crystal Palace come into this London derby off the back of a disappointing 1-1 draw against Brighton & Hove Albion.
Jordan Ayew is still self-isolating after contracting COVID-19 on international duty and will play no part in Saturday's match.
Fulham sit bottom of the table with just one point from five games. Scott Parker's side will be desperate to get a result from this match, as they look to pick up points in the relegation dog-fight.
Eagles predicted line-up
Vicente Guaita, Joel Ward, Cheikhou Kouyate, Mamadou Sakho, Tyrick Mitchell, Jairo Riedewald, James McArthur, Jeffrey Schlupp, Eberechi Eze, Wilfried Zaha and Michy Batshuayi.
Goalkeeper - Guaita
Despite the recent signing of Jack Butland from Stoke City, Vicente Guaita will keep his place in the starting line-up. The reliable Spaniard continues to prove his worth in the Eagles' net.
Defence - Ward, Kouyate, Sakho, Mitchell.
Palace were defending for large parts of the game against Brighton last week, for the majority of it they looked pretty solid, however, conceding a 90th-minute equaliser diminished any defensive efforts.
Roy Hodgson, who was speaking to the press ahead of the Eagles' trip to Craven Cottage, confirmed that Gary Cahill will be unavailable for selection after picking up a slight knock from Lewis Dunk's red card offence last weekend. Mamadou Sakho will be the likely candidate to come in and take his place.
Youngster Tyrick Mitchell continues to impress from left-back and has been one of Palace's impressive standout performers in the early stages of this season.
Midfield - Riedewald, McArthur, Schlupp, Eze.
Palace fans will be desperate to see more of summer signing Eberechi Eze. Hodgson started Andros Townsend ahead of him last time out, but the eagles were lacklustre going forward.
Eze provides a creative spark for a team that struggles higher up the pitch.
Jairo Riedwald played well against Brighton and should keep his place alongside McArthur and Schlupp.
Forwards - Zaha and Batshuayi
The Eagles main man Zaha will start up top with on-loan Michy Batshuayi.
The Ivorian, although quiet last week has had a good start to the season and is central to all of Palace's creative outlet going forward.
With Jordan Ayew still out, Michy Batshuayi will lead the line. The Chelsea Loanee has had a slow start to his second spell at Selhurst Park but with Hodgson's options limited, he looks set to start.