Northampton will welcome the Latics to Sixfields on Saturday a point clear of the League One relegation zone, off the back of a well-earned point against Fleetwood Town on Tuesday night.
Meanwhile, Wigan will make the trip down the M6 on Saturday two points adrift of safety and will be low on confidence having been beaten 5-0 by Blackpool in midweek.
Northampton will be without a couple of key men on Saturday. Both Alan Sheehan and Jack Sowerby are expected to be out, but manager Keith Curle is hopeful that the pair will return to full fitness in the next week or so.
One of the Cobblers January acquisitions, Mickel Miller, will miss Saturday's game having suffered a tear in his hamstring against Lincoln City last weekend. The Rotherham United loanee was substituted off just 35 minutes into his Cobblers debut and is expected to be out for up to three weeks.
As for the visitors, interim boss Leam Richardson will be boosted by the signing of Funso Ojo on Saturday afternoon. Ojo joined the Latics on lean from Aberdeen on Thursday and will hope to add to Wigans midfield options.
Richardson has already seen an overhaul of players this month at the DW Stadium with Tendayi Darikwa, Zach Clough and Corey Whelan joining the club on free transfers, as well as George Johnston on loan. Richardson has told the Manchester Evening News that he is optimistic his side can win on Saturday despite the fact he is still implementing his ideas on the training pitch.
Northampton Town: Mitchell, Kioso, Bolger, Horsfall, Jones, Mills, McWilliams, Morris, Hoskins, Edmondson, Rose.
Wigan Athletic: Jones, Darikwa, Whelan, Johnston, Pearce, Perry, Merrie, Lang, Keane, Ojo, Joseph.
Ones to watch
Northampton's most recent addition, Peter Kioso, will be one to watch on Saturday afternoon. The Irishman added a real attacking threat down the right-hand side for the Cobblers in midweek against Fleetwood.
Kioso was brought in on loan from Luton Town. The defender spent the first portion of the season in League Two at Bolton Wanderers, before Luton recalled him, sending him up a division to League One. During his time in the fourth tier, Kisoso was a success, getting himself on the scoresheet three times and grabbing an assist.
The Cobblers have struggled to find a balance in the wingback positions this season but with Kioso on the right and Joseph Mills down the left, the pair should be a force to be reckoned with for the rest of the season.
As for the Latics, Callum Lang will be the one to watch at the top end of the pitch. Lang will be looking to make a name for himself in the third tier after making a good impression with Morecambe and Oldham Athletic in League Two, scoring 26 goals over two seasons with the northwestern sides.
The striker spent the first half of the season at Scottish Premier League side Motherwell, where he got a taste of European action. Lang scored twice in three games for Motherwell in Europa League Qualifying. His league form wasn't so impressive, but since joining the Latics he netted against Rochdale in Wigans last away trip and will be hoping to do the same against the Cobblers on Saturday afternoon.
Since the sides first met in October 1987, there have been 36 meetings between the clubs. The record swings heavily in favour of the Latics, with 18 wins, 12 draws and six Northampton wins.
The two sides have already been to battle this season. Goals from Danny Rose, Sam Hoskins and Caleb Chuckwuemeka earned the Cobblers a 3-2 win at the DW.
Where to watch
Northampton Town season ticket holders can watch the game for free Iive on iFollow.
Cobblers fans who don't own a season ticket can pay £10 to watch the game live on iFollow.
Wigan fans hoping to watch the action can do so for £10 on Latics TV.
Cobblers boss Keith Curle has been reflecting on his sides recent performances of late and told the Northampton website about the importance of Saturday's match.
Some might say that one point from two games might not be a lot to shout about on the face of it but we’ve had two performances with lots of positives,” he said.
“There are still areas where we can improve but the performance levels this week have been good and we know that there is still more to come from this group.
“The clean sheet at Fleetwood was very pleasing and we created the best two chances in the game. We’ve had a limited amount of training time with the new players but they have all integrated themselves into the group very well.
“It’s a big game against Wigan, they had a bad result on Tuesday night but they were unbeaten in their last five games before that.
“They will be hurting from that result and looking to make amends so we know we are in for a difficult game."
Wigan interim boss Leam Richardson, has highlighted the importance of getting more bodies in, to increase competition in the squad. He told the Manchester Evening News:
“We’re in a certain position where I think a lot of people thought we’d probably be a lot worse off, so we’ll take the positives, even off the back of the Blackpool result, we’ll take the positives that we’re still here, we’re still competing and we want to make them small steps forward.
“Fingers crossed we can add a few bodies to the group because it’s important, not only because we’re kind of low on numbers anyway with the restrictions that surround us with administration and embargoes etc, but we’re trying to add that little competition for places because it’s healthy."