Mikel Arteta's side put on an emphatic display in a 3-1 win over Leicester City last time out with impressive performances from the likes of Willian, Nicolas Pépé and Alexandre Lacazette.
Meanwhile Burnley gained a well-deserved point against the Foxes and Sean Dyche's men will be aiming to complete their first league double over the Gunners since the 1962/63 campaign.
Here are the predicted line ups for both sides.
The Clarets will be aiming to field the same back line following a solid display against Leicester last time out, with the likes of James Tarkowski partnering Ben Mee in central defence whilst Nick Pope will retain his place as Burnley's first-choice goalkeeper.
Jack Cork suffered a hamstring injury against the Foxes and remains a doubt for Saturday's fixture, meaning Dale Stephens, who was signed from Brighton & Hove Albion, should take his place and partner Ashley Westwood in midfield.
The dynamic Dwight McNeil should start on the wing, whilst Jóhann Berg Gudmundsson could return from injury and start on the right-hand side.
Burnley will continue to be without their talisman and top-scorer Ashley Barnes, so Chris Wood will likely partner either Jay Rodriguez or Matej Vydra up top.
Burnley Starting XI: Pope; Lowton, Tarkowski, Mee, Taylor; Gudmundsson, Westwood, Stephens, McNeil; Wood, Rodriguez.
The Gunners have enjoyed a rare period of rest having not played since Sunday and have a near full strength team to choose from.
Bernd Leno is Arsenal's undisputed number one and will start between the sticks, whilst Rob Holding and Gabriel Magalhães should partner each other at the heart of the defence.
They will be flanked by Cedric Soares and Kieran Tierney, with the former impressing in recent weeks when starting at right-back.
The return of Thomas Partey will be a huge relief for Arteta, who will look to partner the former Atlético Madrid man with Granit Xhaka in Arsenal's midfield.
Emile Smith Rowe sustained a hip injury against Leicester and is a doubt for the trip to Lancashire, meaning Real Madrid loanee Martin Ødegaard could feature in the attacking midfield slot.
Arsenal's manager has a welcome selection headache in the attacking areas with a plethora of players in good form. Bukayo Saka is expected to start on the right-wing with one of Pépé or Willian playing on the left, meanwhile Pierre-Emerick Aubameyang could feature up front.
Arsenal Starting XI: Leno; Cedric, Holding, Gabriel, Tierney; Partey, Xhaka; Saka, Ødegaard, Pépé; Aubameyang.
Arsenal have started to find their attacking rhythm in recent fixtures which has seen them score six goals in their last two games.
Burnley, on the other hand, have found goals hard to come by this season, with only Sheffield United scoring fewer than Burnley's 19 goals in 27 Premier League games.
However, the Gunners haven't kept a clean sheet in their last seven games across all competitions which will give the Clarets some hope.
Nevertheless, Arsenal are unbeaten in their last eight league visits to Turf Moor and will be hopeful of continuing their push to get into the top-four.
Prediction: Burnley 1-3 Arsenal