The Baggies currently sit second bottom of the Premier League table, nine points away from safety, but a win against the Magpies tomorrow can cut that points gap to six.
Sam Allardyce's side have only managed to record three wins in the league all season and at the moment they obtain the joint-worst home record in the division, after only earning ten points from a possible 42 in games played at the Hawthorns so far this season.
Meanwhile, Newcastle are on a bad run of form themselves, after not picking up a win in three games and they are situated dangerously close to the drop zone themselves as they are only three points clear of the bottom three.
The last time Steve Bruce's side earned a victory was when they overcame Southampton 3-2 at St James' Park, but they have not won on the road since the end of January when they secured a surprising 2-0 win over Everton.
In fact, Newcastle have been pretty poor on their travels all season as they hold the third-worst away record in the top-flight after only managing to pick up 11 points from 13 games that they have played away from home.
With points desperately needed to be accumulated on to the board if the Baggies hope to have any chance of achieving Premier League survival, Allardyce will be welcome to the news that his squad have no fresh injury or suspension concerns.
The only remaining doubt being full-back Kieran Gibbs who has been out of action since the end of January with a neck and shoulder problem.
In good news for the Baggies, winger Robert Snodgrass returned from his knee injury on Thursday night after coming on as a second-half substitute.
Whereas for the away side, dangerous attacking players Callum Wilson, Miguel Almiron and Allan Saint-Maximin will all be sidelined by injuries.
Therefore it is likely that Joelinton will start in the central striker role with Arsenal-loanee Joe Willock showing support for the forward as an attacking midfielder.
With Matt Ritchie reportedly clashing with Bruce during the week, it is unlikely that the wide player will feature at all in tomorrow's trip to the Hawthorns.
Ones to watch
Mbaye Diagne- West Bromwich Albion
Despite only scoring one goal in his seven games for the club since joining in the January transfer window, Diagne has provided the Baggies with a focal point and dangerous going forward.
With the pace and strength that he possesses, he is always going to cause trouble and worry to any opposition defence with only his confidence in front of goal the only thing that is lacking.
The Senegalese did have a goal chalked out late on for offside last time out and that no doubt would have boosted his confidence ahead of the clash with Newcastle.
However, if over the next couple of games if can compliment his decent showing with a couple of goals, he could be a huge factor and a way in which Allardyce's side will look to make a great escape.
Joe Willock- Newcastle United
The 21-year-old midfielder has started in all four games since joining the Magpies in January and has been a rare bright spark in what has been a recent tough spell for Bruce's side.
Willock always looks lively when fed the ball and is never afraid to drive forward and bring more of Newcastle's players into the games.
Especially with the absences of key players such as Saint-Maximin and Almiron, tomorrow afternoon the Arsenal loanee could actually be the main outlet in terms of the visitors creating chances.
However, if he turns out to have an off day or things just do not turn out for him, this would be a worry for the Magpies and ultimately it could end up being a long and miserable afternoon for Newcastle.
In the reverse fixture back in December, a late strike by Dwight Gayle earned a 2-1 win for Newcastle and three points tomorrow would mean a first double over the Baggies since the 2008/09 season.
Newcastle have actually won the last two fixtures against this weekend's opponents after winning 3-2 at the Hawthorns last season in the fifth round of the FA Cup.
However, West Brom have accumulated seven points from their previous four top-flight home games against Newcastle after winning two, drawing and losing one each.
This is in fact a single point more than they had from their first seven Premier League games that they played against each other.
West Bromwich Albion:
Johnstone; Furlong, O'Shea, Bartley, Townsend; Snodgrass, Maitland-Niles, Yokuslu, Gallagher, Pereira; Diagne
Dubravka; Murphy, Lascelles, Clark, Lewis; Hendrick, Hayden, Shelvey, Fraser; Willock, Joelinton
Where to watch on TV
The Premier League encounter which kicks off at 12 PM tomorrow is being streamed live on Amazon Prime.