Sean Dyche's men have a good record when playing this weekend's hosts away from home, taking points from the Theatre of Dreams on their past four visits, so this won't be a 'walk in the park' for United.
In the reverse fixture, Solskjaer's men claimed the victory, in a hard fought game that was won with a volley from Paul Pogba, in the 71st minute.
Marcus Rashford (ankle) may miss here for United, as he faces a 'late fitness test on Sunday morning' according to Solskjaer.
Ivory Coast international Eric Bailly, is in contention for a return after testing positive for COVID-19 earlier in the month.
Thursday's Europa League suspended trio, Luke Shaw, Harry Maguire and Scott McTominay are all expected to return to the side.
Anthony Martial (knee) will be absent once again, and is currently expected to miss the remainder of the season.
Ones to watch
Edinson Cavani is another striker in-form heading into this game, with the Uruguayan scoring against Tottenham and Spanish side Granada, in the past week.
His aerial prowess will be sure to challenge a Burnley defence that is extremely competent at clearing crosses.
Vydra netted once again last week in the loss to Newcastle, and his speed gives Burnley a different option if their gameplan fails to come off.
Manchester United: Henderson, Wan-Bissaka, Lindelof, Maguire, Shaw, McTominay, Fred, Pogba, Fernandes, Greenwood, Cavani.
Burnley: Peacock-Farrell, Lowton, Tarkowski, Mee, Pieters, Brownhill, Cork, Westwood, Gudmundsson, Vydra, Wood
Where to watch
The game is expected to kick off at 4:00pm GMT on Sunday, and can be viewed on both Sky Sports Main Event and Sky Sports Premier League.