Reading got beaten 3-2 by Stoke City after a late 85th minute winner cost them a point, while Swansea lost 2-1 to Blackburn Rovers, with a debut second-half goal from Jamie Paterson not enough to complete a comeback from the Swans.
Both sides will now focus their attention away from the league and focus on progressing in the Carabao Cup.
Reading will most likely be without a number of key attacking players due to minor injuries, and manager Veljko Paunovic won't be looking to risk players with such a thin squad.
Ovie Ejaria missed the game against Stoke due to a groin injury that he picked up in their last pre-season friendly against Crystal Palace. John Swift and Lucas Joao came off late on at the weekend after struggling with cramp and a dislocated shoulder respectively, so are unlikely to be risked.
Yakou Meite will be out until 2022, while Felipe Araruna hasn't returned to training after recovering from a knee injury.
Swansea are likely to rotate a little as new manager Russell Martin will want to fully assess his squad after being appointed the day after their final pre-season game.
They will have to make do without midfielder Korey Smith after he was taken off with injury against Blackburn on Saturday.
They are likely to rotate goalkeepers, but with backup goalkeeper Ben Hamer contracting coronavirus, it's likely youngster Nico Defreitas-Hansen will get a rare start.
Southwood; Yiadom, Dorsett, Holmes, McIntyre, Tetek, Rinomhota, Bristow, Azeez, Camara, Puscas.
Defreitas-Hansen; Latibeaudiere, Bennett, Cabango, Naughton, Grimes, Dhanda, Cooper, McFayden, Whittaker, Joseph.
Ones to watch
The Serbian midfielder is highly rated at Reading and at national level, but opportunities have been hard to come by.
With the brilliant midfield duo Andy Rinomhota and Josh Laurent ahead of him, he has struggled to play, but with Reading's thin squad this season, he will get more playtime.
At 18 years old he already shows so much aggression and confidence on the ball, and also makes great runs through the lines.
The 20-year-old has a wonder of a left foot, with great finishing and dribbling ability. The question is whether he can capitalise on an opportunity and start being a regular in the first team. he has bags of potential, so at 20 he needs to start utilising it.
These two sides have plenty of history, with the most memorable match being the Championship Play-off final in 2011, where Swansea gained promotion to the Premier League for the first time when they defeated Reading 2-4 at Wembley, with Scott Sinclair scoring a hat-trick.
The last time these two sides met however was back at the end of April, where a late 93rd minute equaliser from former Reading loanee Tomas Esteves wasn't enough as a 2-2 draw meant that Reading missed out on the play-offs, while Swansea secured their play-off spot.
How to watch
The game is unavailable to watch in the UK on TV, however, you can watch it for £10 on Reading's website if you live overseas.