The Tigers began life back in the second tier with a resounding 4-1 victory at Preston North End which was followed up by a penalty shootout defeat to League One outfit Wigan Athletic in the first round of the Carabao Cup.
The Tigers will be without last season's top scorer Mallik Wilks as he picked up an calf injury in the victory at Preston as will midfielder George Honeyman, out with an ankle issue. Left-back Callum Elder is fit again after recovering from a thigh problem while Ryan Longman, Tommy Mayer, Sean McLoughlin and Randell Williams are all available following recovery from COVID-19.
Luke Amos, Ilias Chair and Sam McCallum all returned to training this week and will be further assessed to see if they will be available. Sam Field underwent knee surgery and remains out while manager Mark Warburton will likely name an unchanged lineup from the draw against Millwall.
Hull City: Ingram; Jones, Greaves, Emmanuel; Docherty, Smallwood; Wilks, Moncur, Lewis-Potter; Magennis
Queens Park Rangers: Dieng; Barbet, Wijs, Dickie; Wallace, Johansen, Ball, Odubajo; Willock; Dykes, Austin
Ones to watch
The Hull midfielder was instrumental in the Tigers' runaway victory at Preston with a goal and an assist. His work ethic and speed on the left side of the midfield could prove to be the creative force Hull needs as they are set to be without Wilks for a few weeks.
A brilliant performance in the heart of the QPR defense. He leveled after bringing the ball out of defense and sprinting up the field. He also closed down numerous attacks by the Lions in what was a superb all-around performance.
The visiting side has won the last four matchups with Hull emerging 2-1 winners in December of 2019. Chair gave QPR a 20th-minute lead with a low shot into the bottom corner.
The Tigers equalized in the 32nd minute after Joe Lumley spilled a cross by Josh Bowler that Honeyman was on hand to tap home. Lumley later saved from Bowler to keep the Hoops on level terms.
It looked as though the points would be shared until a free-kick by Jarrod Bowen was met by Jackson Irvine, who was unmarked at the near post and he diverted it in for the winner a minute from time.
How to watch
While there will be no television coverage of the match, fans can follow the action by registering on each club's website. For Hull, it's iFollow Tigers and for QPR, it's QPR+. Kick-off is set for 15:00 BST.