The hosts will look to bounce back after a disappointing 2-1 loss to play-off chasing last time out.
Six points separate the two sides, with 's side sitting just two places about Reading in the table.
The hosts will once again be without talented right winger as he remains out with a leg injury.
Andy Rinomhota will not be available for the Royals as he remains out with an ankle injury.
Yakou Meite continues to work his way back into the side following a spell out injured, and may feature on Saturday after a six-minute cameo against last time out.
remains absent as his departure from the club seems imminent.
Baxter, Jones, McLoughlin, Greaves, Longman, Slater, Smallwood, Elder, Lewis-Potter, Honeyman, Sayyadmanesh.
Nyland, Yiadom, Morrison, McIntrye, Baba Rahman, Ince, Drinkwater, Dele-Bashiru, Hoilett, Laurent & Joao.
Ones to watch
The 21-year-old has been the Tigers' best player by some way in their return to the Championship after a stint in last campaign.
With nine goals and four assists, the youngster is the club's top scorer and has not missed a single minute of action for this season.
It is easy to see why - if rumours are to be believed - there are a number of clubs interested in acquiring his services in the summer.
Despite missing 22 games with a hip injury, Lucas Joao has been instrumental to 's season so far.
With 10 goals and three assists, the forward has played a huge role in their fight against relegation, and things will have been much worse for the Royals without him.
has more than stepped up in the absence of Swift, with four goals and an assist in his last three appearances.
The two sides shared the points last time out, when their December 4 contest ended 1-1, with Hull's Wilks' second half strike cancelling out Tom Holmes' opener.
The visitors have won just one of the last 10 meetings between the two, with the Tigers emerging victorious on five occasions and four draws.
How to watch
The game will kick off at 15:00 BST at the in Hull, England on Saturday, April 23.
Fans outside of the UK and Ireland can purchase match passes on either of the clubs' websites.
Audio match passes will be available for fans in the UK and Ireland to purchase on either of the clubs' official websites.