Giovanni van Bronckhorst's Light Blues suffered a disastrous start to UEFA Champions League qualifying as they went down 2-0 to the Belgians in their Third Qualifying Round, First Leg tie at the King Power at Den Dreef Stadion a week ago. Teddy Teuma fired Union Saint-Gilloise into a first half lead before Dante Vanzeir's second half penalty left Rangers' European dreams very much on a cliff edge.
Rangers bounced back from that defeat with a 2-0 victory over Kilmarnock at Ibrox in the cinch Premiership on Saturday while Union Saint-Gilloise endured a tough time at Mechelen as they were defeated 3-0, that loss being their first in the Belgian Pro League this season.
Van Bronckhorst could opt to keep faith with a winning team following that victory over Kilmarnock on Saturday. Ridvan Yilmaz, Steven Davis, Tom Lawrence and Scott Wright all came into The Gers side as they continued their winning start to the domestic campaign.
Forward Alfredo Morelos made a scoring return as a substitute against Kilmarnock and he could be pushing for further minutes following injury.
Ianis Hagi, Filip Helander, Kemar Roofe, Nnamdi Ofoborh, Stephen Kelly, Niko Katic and Jack Simpson will play no part for the Glasgow giants.
Union Saint-Gilloise head coach Karel Geraerts could make changes to his side following that 3-0 defeat to Mechelen. Ross Sykes, Sanne Lynen and Simon Adingra are amongst those players who could be considered for recalls.
The Belgian club are set to be without Ismael Kandouss, Koki Machida, Dennis Eckert Ayensa and Gustaf Nilsson.
Rangers: McLaughlin, Tavernier, Goldson, Sands, Ridvan, Lundstram, Davis, Tillman, Lawrence, Wright, Colak
Union Saint-Gilloise: Moris, Van der Heyden, Burgess, Sykes, Lapoussin, Amani, Teuma, Lynen, Nieuwkoop, Vanzeir, Adingra
Ones to watch
Antonio Colak (Rangers)
Big things are expected from the Croatian international forward who joined Rangers on a three-year deal last month. Colak will be hoping that the goals will now flow in the famous blue shirt after getting off the mark against Kilmarnock at the weekend.
Dante Vanzeir (Union Saint-Gilloise)
Belgian attacker Vanzeir has netted an impressive 33 league goals in two seasons with Union Saint-Gilloise. A goal for Les Unionistes at Ibrox would really cause the hosts further problems and Vanzeir seems like the player most likely to find the back of the net for the Belgian side.
Last Tuesday's meeting in Heverlee was the first between the two clubs.
The 2-0 defeat to Union Saint-Gilloise was Rangers' second loss in 11 games against Belgian opposition in Europe.
This season's European adventure is Union Saint-Gilloise's first in 58 years.
How to watch
The UEFA Champions League Third Qualifying Round, Second Leg tie between Rangers and Union Saint-Gilloise has not been selected for live broadcast. Fans can stream the game live by subscribing to RangersTV.