Claudio Ranieri's side are celebrating a fairytale title triumph, while Everton are enduring another largely frustrating season for the second successive season leaving Roberto Martinez's future at the club uncertain.
Everton have lost just once in the last 12 Premier League contests with Leicester, but this was the reverse fixture in December. The Toffees were defeated 3-2 at Goodison Park last December, with PFA Player of the Year Riyad Mahrez bagging a brace to ensure that the Foxes topped the table at Christmas.
The statistics point towards a draw on Saturday as 68 per cent of Premier League games between the two sides have been drawn, the highest ratio of any fixture in the history of the competition that has been played more than 10 times, and the last five meetings at Leicester have all ended level.
No party feeling for Everton and Roberto Martinez
While Leicester have very little to play for and will be very much in party mood, Roberto Martinez will be hoping his side can pick up three points to appease supporters who have been getting more and more frustrated and their patience with the Everton boss has all but run out.
Two painful semi-final defeats in both domestic cups, coupled with another largely frustrating league campaign has made the 2015/16 season one to forget for the Blues. Victory over Bournemouth last time ended a seven game winless streak, but did little to silence Martinez's critics and a number of supporters remained inside Goodison Park following the match calling for the Spaniard to end his three-year tenure on Merseyside.
Everton's away form this season suggests they could cause an upset at the title party, but inconsistency has plagued their season. Roberto Martinez's side have been impressive on their travels, losing just three of their last 18; a record which is all the more notable given the Blues have won just twice in 11 league matches at Goodison Park. However, they have failed to win any of their last four games away from home.
Roberto Martinez will be hoping his side can finish the season strongly with their final two games against relegation threatened Sunderland and Norwich City. However, how the Blues fare between now and the end of the season may be irrelevant as the pressure continues to mount on the shoulders of Martinez.
Last season this was Leicester's first fixture after a 10 year absence from the Premier League and the Foxes had only four men with top-flight experience. This time Everton will give the newly crowned champions a guard of honour after Claudio Ranieri's side achieved the seemingly impossible feat of winning this seasons Premier League title despite being 5000/1 at the start of the season.
The Foxes will be keen to avoid defeat on Saturday as they play in front of their home supporters for the first time since completing the remarkable achievement and captain Wes Morgan and his teammates will lift the trophy following Saturday's clash.
En route to lifting the Premier League trophy, Leicester have lost just once at home and only three times in the league in total. Since their last home Premier League defeat when they conceded five against Arsenal in September, the Foxes have conceded just seven goals in 14 games at the King Power Stadium, keeping nine clean sheets in that run.
Everton will be without Gerard Deulofeu after the winger was ruled out for the remainder of the season with a medial knee ligament injury. The Spaniard joins captain Phil Jagielka (hamstring) and centre-back Ramiro Funes Mori (suspension) on the sidelines, while Gareth Barry (groin) and Seamus Coleman (hamstring) are set to be assessed in the lead up to kick-off.
Leicester have now new injury problems, though Danny Drinkwater and Robert Huth will miss the fixture after receiving suspensions following last weekend's 1-1 draw with Manchester United. The Foxes will have striker Jamie Vardy available after completing his suspension following a red card against West Ham United and subsequent additional game for improper conduct.