The Reds travel to the Hawthorns to close out their domestic campaign against the Baggies, hoping to potentially finish as high as sixth - should other results go their way - although the fixture is relatively meaningless in the grand scheme of things.
That's because Liverpool's focus is undoubtedly on their first European final in nine years against Sevilla in Basel on Wednesday night, reflected in Klopp's hopes to field a weakened side against Tony Pulis' team.
Their continental exploits have been prioritised in recent weeks, given the prize of Champions League football for the winners of the Europa League, meaning Klopp has used a stronger XI in the competition, reverting to a much-changed second-string team for their league games.
However, the German fielded a strong side against Chelsea on Wednesday, what is likely to be the same one which starts in Switzerland, as Christian Benteke's stoppage-time header at the Kop end rescued a 1-1 draw.
Klopp to heavily rotate squad ahead of final
As a result, none of those involved in mid-week are likely to play in the West Midlands this weekend. Amongst those in contention to replace Klopp's first-choice starters are back-up goalkeeper Adam Bogdan, who hasn't featured since December, full-backs Connor Randall and Jon Flanagan and midfield trio Kevin Stewart, Jordon Ibe and Joao Carlos Teixeira.
The Reds boss could even hand full league debuts to Sergi Canos and Cameron Brannagan, both of whom have been training with the senior squad at Melwood this week. Canos, who returned from a fruitful season-long loan spell at Brentford in the Championship, could be rewarded with a maiden first-team appearance for the club.
Also expected to take up a place in the match-day squad is Danny Ings, who is bidding to return and make a first appearance under Klopp after being out since October with an anterior cruciate ligament injury sustained in training.
The trip to West Brom also represents a chance for captain Jordan Henderson and Divock Origi to be able to prove their respective fitness and catapult themselves into contention for the squad for the Europa League final. Earlier this week, Klopp admitted the two could be involved if they manage to close in on full fitness in sufficient time.