Thanks for following the live commentary with me this afternoon, until next time, goodnight!
As for the Citizens, they struggled after an encouraging showing in the early exchanges - and didn't particularly respond with much urgency or purpose after Rashford's opener, until it was too late.
FULL-TIME: Manchester City 0-1 Manchester United. Game over, the visitors prevail! United grab some much-needed momentum, as well as belief, in a derby fixture where they didn't particularly dominate but got the job done.
90+6: Yep, it looks all over now.. Rashford wins a corner from Mangala and the clock continues to tick down..
90+5: One minute remains, and this is last-chance saloon time for City now.. United are defending for their lives, they've dealt with the pressure well thus far.
90+3: Fernandinho whips the ball into the area, a fortunate deflection sees the ball drop on the edge of the area - and Bony clatters into Smalling, free-kick given United's way in the process.
90+1: Ooooh, close! Aguero fires narrowly wide after a superb pass by Silva, and City continue in their pursuit of a late equaliser.
90: The fourth official signals for six minutes of stoppage time to be played, on his electronic board. Six minutes for City to salvage something from a game they've struggled to grab a real foothold in, until it was too late in essence.
86: Everyone's dropping like flies now! First Rashford, who's probably suffering from burnout, then Martial in the City half too - as United look to close out the game in the final stages..
83: That's the end of Matteo Darmian's afternoon, after suffering from cramp twice in quick succession. Timothy Fosu-Mensah, one of the club's highly-rated youth prospects, replaces the Italian for the final minutes in his first senior Manchester Derby fixture.
80: Ten minutes to play, and Smalling is fortunate to still be on the pitch! Slides in late on Aguero, and was already previously booked early in the first-half - he'll need to be careful..
75: Mangala goes into the referee's book for a rash challenge on Lingard, who was approaching the final third with intent. He'll have no complaints about the booking, it was cynical but he'll say he 'took one for the team' there.
74: Navas attempts to create something once more on the right-hand side, skipping past Darmian - but his effort swerves over the crossbar.
71: Important block by Carrick! Aguero's header at the far post looks destined for the top corner, but Touré latches onto the ball and feeds Bony from close-range, who is denied a shot on-goal by the English midfielder with a last-ditch sliding block. Still 1-0, the pressure continues to intensify.
69: United's second substitution is taking place now - Bastian Schweinsteiger is introduced into the fray, replacing Juan Mata. van Gaal hoping to see the game out now?
66: OFF THE POST! Touré whips a teasing ball into the area for Aguero, who had a lot to do, who flicks a header goalwards. de Gea is beaten at his near post but watches helplessly as the Argentine's header cannons back off the post, and out to safety. Close again!
65: In the last ten minutes, the hosts have seen plenty of the ball and it's clear that they've now found a spring in their step - they need to equalise soon though, and utilise this spell of attacking pressure to good effect.
63: Great ball by Sagna! City's passing play has finally found some merit - but Bony is unfortunate not to properly connect with the ball after an excellent ball into his path by Sagna from the right-hand side. Close, but no cigar as of yet.
61: Some brief respite for the visitors following a spell of attacking pressure from City, as the substitution is being made now. Marcos Rojo is walking off the pitch, with Valencia replacing him in a like-for-like alteration. Fresh legs!
60: Another set-piece, another one wasted. Goal-kick to come, as cameras focus on Antonio Valencia - who is receiving instructions from a Utd coach on the substitutes' bench, he's preparing to come on shortly.
59: An important sliding block by Darmian! Some patient build-up play almost results in a goalscoring opportunity, but for a last-ditch intervention from the Italian to slide in cleanly and see the ball out for a corner-kick. Pressure continues to rise.
57: Stats - City have totalled 11 attempts on goal, to United's lowly 5 thus far. However crucially, Utd have had 4 on target - one more than City, who've had more than double their shots in the opening hour today. Just goes to show you can take as many shots as you'd like, but if you don't test the goalkeeper, you won't score..
56: Ironic jeers from the home supporters as de Gea's resulting goal-kick flies into the stands near the centre-circle, instead of his intended target.
55: Ten minutes into the second-half and already, the game is starting to open up more. Aguero leaves Blind in his wake before firing narrowly over the crossbar from a near-improbable angle.
54: Martial darts past his marker into the area, attempts to curl a shot goalwards - takes a deflection and Caballero can only parry partially clear with an important diving stop.
52: Another change for the hosts, and their last - Wilfried Bony comes on, in place of Martin Demichelis - who hasn't had the best of games today.
49: A warm round of applause around the ground for Hart, who has to be stretchered off as he's unable to put any weight on the injured leg. Willy Caballero - cup shootout hero - replaces him.
46: Play has halted, Joe Hart is injured clutching his hamstring overstretching for a ball after an underweight back-pass by Demichelis...
Second-half, is now underway! Manchester City 0-1 Manchester United - can the hosts snatch a point or even three? Or, can van Gaal's side grab bragging rights at the Ethiad? We're 45 minutes away from finding out!
HT: Without Otámendi and Kompany at the back, they look disorganised and certainly not full of much confidence either. It's disappointing to see and even with the injured Wayne Rooney watching on from the stands, he'd certainly be relishing this type of fixture with the aforementioned pair unavailable for selection.
HT: City are definitely playing like a side that are in the lead, they've got no urgency at the moment and are playing right into United's hands. The visitors have stuck to the task asked of them - looking dangerous on the counter and a handful for City's backline - especially Demichelis - to deal with.
HT: United have a slender advantage of their own, courtesy of a cool finish from Marcus Rashford - becoming the youngest goalscorer in the Manchester Derby, and he'll be proud of that achievement as well as his overall contribution thus far.
HT: It's half-time, in what has been a less-than-exciting but intriguing 45 minutes thus far.
HALF-TIME! Manchester City 0-1 Manchester United.
On the stroke of half-time, Rashford goes down inside the area under the challenge of Demichelis. The centre-back reacts angrily to the challenge, insisting that the teenager went down too easily - and they clash with a number of players from their respective teams getting involved. Replays show there was contact, and Demichelis was lucky not to have been penalized for that there.
45+2: It's all kicking off here now suddenly! Penalty appeal, not given!
45: The fourth official signals for two minutes of stoppage time to be played on his electronic board.
43: Blind is given a talking to by referee Michael Oliver after an accumulation of fouls on Aguero, they seem to have some sort of battle going between the two now..
41: Blind goes down clutching his leg after a 50-50 challenge between himself and Aguero - foul awarded but no card, it was accidental and both players went for the ball itself.
40: Touré's tireless work goes unrewarded as Mata - usually sloppy himself - wins the ball back full of exuberance for his side in their half.
39: Another poor cross, this time from Darmian as City lose possession in their own half and are almost punished for it. If only.
38: For a side that have a one-goal deficit to overturn, City aren't doing enough to get themselves back in the game. You just naturally expect more of a reaction from these players, apart from Navas and one or two others, haven't really seen that yet.
37: Rojo with a dangerous cross into the area, headed clear by Clichy with Mata lurking behind him. Throw-in taken with no real urgency by Darmian as United look to see out the first-half's action at their own tempo.
36: Another corner, another disappointing delivery - this time from Silva as United scamper the ball clear and win a free-kick in the process.
35: Navas goes one-on-one with Rojo and weaves past him, before a deflected effort trickles out for a corner.
34: Another corner-kick comes of nothing, this time from City's perspective as Navas' delivery is flicked into the gloves of de Gea. Service has been disappointing from set-pieces thus far, and although it's a derby fixture, has been quite flat since Rashford's opener.
32: Wide! Touré curls an effort goalwards after some encouraging play down the right by Navas, but his shot doesn't have enough bend to swerve into the far corner and de Gea sprawls to his right - watching on as the ball floats narrowly wide of the target.
31: Daley Blind fizzes the ball into the area, but nothing comes of the chance and City relieve pressure on their goal.
30: Half-an-hour gone, United are leading. Just the one goal for the moment, but they've got a corner-kick with plenty of players edging towards the area.
25: And so, here's confirmation of the change... Fernando comes on in his place, an untimely and unfortunate end to Sterling's first home Manchester Derby.
24: Sterling has been struggling over the past few minutes since returning to the pitch, and it seems as though he's tweaked a groin muscle or injured himself in that area after a late challenge by Mata - Pellegrini will be reluctant to keep him on much longer for fear of aggravating the problem further..
21: Ooooh! Free-kick for City, whipped into the area and United's backline struggle to deal with the ball sufficiently - leaving Demichelis with a free header from close-range. Unfortunately for the experienced centre-back, he flicks his effort wide of the far post.
20: Sterling down on the turf, clutching his groin in some discomfort... he's going to need some treatment from the physios. Game temporarily halted, another goal at White Hart Lane - 2-0 to Tottenham, Kane completes his brace, Dele Alli with the assist. As it stands, Spurs have closed the gap on league-leaders Leicester to just five points.
18: IMPORTANT SAVE, JOE HART! It's truly great footwork from Martial, and he almost doubles the lead! Hart makes a good reaction stop to deny the young Frenchman though, and the danger is averted - at least for now.
Great composure from the 18-year-old, breaks the deadlock and the home end is deadly silent! Having been slipped through by Mata, he did well to skip past Demichelis with ease before slotting home from close-range, despite Hart getting a hand to his curled effort. 1-0, and United are in-front!
16: GOAL! UNITED AHEAD - MARCUS RASHFORD SCORES IT!
14: Good save, de Gea! The Spaniard is forced into a sharp stop with his leg to deny Navas from opening the scoring at his near post, although he would've seen the ball late as his view was blocked by a defender in sight close by.
13: Comes of nothing in the end, as Joe Hart punches the ball clear with confidence as City break with pace and purpose down the other end.
12: The referee has a talking to with some of the players in the area after some clear pushing-and-shoving with a United corner-kick to come.
11: Excellent tackle! Demichelis times his sliding challenge well, and comes away unscathed as Lingard sprints attempting to latch onto the loose ball in a dangerous area.
10: Referee Michael Oliver, who sent Smalling off in an infamous derby back in late 2014, had no real choice there in fairness.
9: First booking of the game, brandished to Smalling after a cynical pull-back on Aguero as the Argentine accelerated past him.
6: CLOSE! First real opportunity for the hosts. Silva slips Sterling through down the left-hand side, with United struggling to get men back quickly enough. He floats a teasing cross into the area, Navas goes for goal but his volley flashes narrowly wide of de Gea's far post.
3: A goal alert to tell you about elsewhere in the Premier League - Tottenham are currently a goal ahead at home against Eddie Howe's Bournemouth side, courtesy of none other than Harry Kane.
2: Lingard attempts to swing a cross into the earlier, cleared away at the first attempt by Mangala though.
1: A chorus of boos reverberate around the Ethiad as United aim to sustain some possession in midfield... it's going to be that type of game, isn't it?
Marcus Rashford makes his 8th consecutive start for the Red Devils, whilst the likes of Adnan Januzaj and Timothy Fosu-Mensah are amongst the substitutes' bench for the visitors this afternoon.
In terms of tactics, both teams start with a 4231 formation - looking to be compact out of possession and counter at speed against their opponents.
The two teams are waiting patiently in the tunnel, and you can just tell the atmosphere is continuing to build inside the stadium itself.
Meanwhile, United make two changes of their own. Marouane Fellaini drops to the substitutes' bench with Michael Carrick making his 450th Premier League appearance today, whilst Morgan Schneiderlin is back in the fray with an intriguing midfield battle awaiting the talented Frenchman.
As previously stated, the centre-back pairing of Kompany-Otámendi isn't present today, neither are fit and available for selection. In their place, Eliaquim Mangala and Martin Demichelis. Two other changes to the side that drew against Dynamo Kyiv in midweek, with Yaya Touré and Raheem Sterling back in the starting XI.
Manchester United: de Gea; Darmian, Smalling, Blind, Rojo; Schneiderlin, Carrick; Lingard, Mata, Martial; Rashford. Subs - Romero, Fosu-Mensah, Valencia, Fellaini, Schweinsteiger, Januzaj and Depay.
Manchester City: Hart; Sagna, Demichelis, Mangala, Clichy; Fernandinho, Touré; Navas, Sterling, Silva; Aguero. Subs - Caballero, Zabaleta, Kolarov, Fernando, Manu Garcia, Bony and Iheanacho.
Both sides will be eager for victory - City can maintain their faint title aspirations with a win whilst United can breathe new life into their quest for Champions League qualification, after they were knocked out of the Europa League at the expense of Jürgen Klopp's unpredictable Liverpool side.
Ronald Koeman's men have propelled themselves level on points with United as a result, whilst the Tyne-Wear derby served up an unpredictable 1-1 draw at St. James' Park in the 1.30pm kick-off.
In terms of results earlier on, Southampton managed a miraculous comeback from two goals down to seal a 3-2 victory at home against Liverpool.
So, what's at stake? City can close the gap on third placed Arsenal with a derby day victory, whilst United can leapfrog West Ham into 5th - just a point behind the sky Blues (provided they win!).
Following injuries to City's first-choice defensive partnership of Nicolas Otámendi and captain Vincent Kompany, it is expected that the Red Devils will hope to prevail and exploit the Citizens' defensive frailties away from home today.
Manchester City host local rivals United, in what promises to be an intriguing fixture - especially with the early team news that awaits.
Hello everyone! Good afternoon and welcome to VAVEL UK's live commentary from today's Manchester Derby at the Ethiad.