Southampton stars Ryan Bertrand and Shane Long are likely to spend at least the next few weeks on the sidelines, as they both suffered hamstring injuries whilst playing for their countries in World Cup qualifying.
Long limped off the field after an hour during Ireland's 3-1 win over Moldova, whilst Bertrand only lasted 19 minutes of England's 2-0 victory against Malta.
Saints fans now have to wait nervously to see how long the duo will be out of action and with the injuries both being in the hamstring area, it could be a while before Claude Puel can select the pair again.
Long's injury came after he broke his 1,226 minute goalscoring drought by netting Ireland's opener inside two minutes. He was then involved throughout before being replaced by youngster Callum O’Dowda. Long reportedly tweaked his hamstring in the last fixture against Georgia but was declared as fit to play last night.
Bertrand's absence means he joins the long list of England stars who have had to withdraw from Gareth Southgate's first national squad. The 27-year-old signalled to the bench he could not continue very early into the Three Lions' easy win over Malta.
The pair are highly unlikely to feature against Burnley this weekend and may even miss Southampton's highly anticipated trip to Inter Milan.
Despite two key players picking up injuries, it wasn't all doom and gloom for Saints fans during the international window. Midfielder Dusan Tadic continued his fantastic run of form by scoring Serbia's winner in the 3-2 victory over Austria. The Serb now has three goals in as many World Cup qualifying games.
After goals against Moldova and Ireland earlier in the campaign, Tadic now sits on 11 international goals in 41 appearances. The 27-year-old has been in fine form in the Premier League this season and has arguably been Southampton's best player.
Saints fans will be hoping he can continue this purple patch when he returns to club football.