Six points adrift, to say the hosts need to win would be an understatement, with them praying on the Swans producing a performance with an 'end-of-season' vibe to it.
However, with so much doubt surrounding the role of manager at the Liberty Stadium as we head into the summer, some of these players are playing for their futures as they look to impress the current boss, Francesco Guidolin, or anyone watching on who could step into the position of power before the new season.
Plenty to play for amidst plenty of speculation
Rumours have really began to circulate this week regarding Guidolin's future.
With Swansea in talks regarding a potential takeover, there have been suggestions from the media that the American duo hoping to invest in the club are keen on Brendan Rodgers returning, while other outlets have said they want to see Marcelo Bielsa take the role instead.
Both were linked with the Swansea job when Garry Monk was sacked at the back end of last year, but Guidolin has stepped in and steered the Jacks to safety and certainly appears to have earned himself a chance from the start of next season - and the players believe so too.
Either way, the players in South Wales will be hoping they are still around for the new campaign too and so are unlikely to drop their performance levels even with safety seemingly assured.
Desperate times for the opposition
In the other dugout, Rafael Benitez's future is uncertain too. It seems that he will not be staying on Tyneside if Newcastle are relegated, and that is becoming increasingly likely with the Spaniard yet to win a game since taking the job in the North East.
His record with the Magpies so far reads three defeats and one draw, while Swansea come into this game looking for their fifth win from their last seven outings.
Last week's 1-0 success over reigning Premier League champions Chelsea was labelled as the team's best performance of the season by Guidolin, and with the pressure of relegation off their backs now, they can play with freedom as they travel to Newcastle on Saturday.
Same XI that shocked the Blues?
Swansea have won six of their last seven meetings with the Mags, but they could be without key man Leon Britton as they pursue a third consecutive success over them this weekend.
The midfielder has struggled with a back problem throughout the season and is a doubt for this fixture as a result, having missed last week's win over the Blues.
After that latest performance, it would be a surprise to see Guidolin change his team at all in truth, and so the Italian could name the same XI - one which sees Jefferson Montero operate on the wing after a long time out-of-favour.
Newcastle come into the game off the back of a 3-1 defeat to Southampton, and so one would expect Benitez to switch things about. However, with the treatment room still housing a number of players, there's not a great deal of tinkering he can do.