Dortmund come into this tie having suffered a 1-0 loss to Bayern last time they took to home turf. Without the crucial services of Marco Reus, they fell to a sole strike from Joshua Kimmich which all-but-officially sealed the race for the Bundesliga title.
The visitors, Hertha, are enjoying a fresh start to their Bundesliga campaign under the new tenure of Bruno Labbadia. The German is the fourth manager to have taken charge of Die Alte Dame this season, and he has turned their fortunes around since the resumption of the league with a four-game unbeaten run that has seen them claim a staggering 10 points from a possible 12.
The string of good results has propelled Hertha up the standings into Europa League contention, having been loitering around the relegation zone only a matter of weeks ago.
The hosts will be without Reus for a while longer as he continues his recovery from a groin injury. Mats Hummels will miss out due to suspension following the reception of a fifth yellow card this season last time out.
The big question surrounds the fitness of youthful starlet Erling Haaland, who suffered a knee injury in the blockbuster match with Bayern. The Norwegian did not feature in Paderborn last week, but the additional recovery time may see him ready to go again on Saturday.
Hertha’s ever-increasing injury list rules out seven players, including linchpin forward Matheus Cunha and first-team regular Marvin Plattenhardt, both of whom suffered concussions in the 2-2 draw with RB Leipzig almost two weeks ago.
Borussia Dortmund: Burki; Piszczek, Schmelzer, Akanji; Hakimi, Can, Witsel, Guerreiro; Brandt, Sancho, Hazard. (3-4-3)
Hertha Berlin: Jarstein; Pekarik, Boyata, Torunarigha, Mittelstadt; Grujic, Skjelbred, Lukebakio, Dilrosun; Ibisevic, Piatek. (4-4-2)
Ones to watch
Jadon Sancho is the man to keep an eye on for Borussia Dortmund. Scoring his first career hattrick at the weekend brought his tally to 17 in the Bundesliga this season, a remarkable feat that, when coupled with his assists, places him second across Europe’s major divisions in terms of total goal contributions.
Hertha Berlin’s man of the moment, Krzysztof Piatek, is one to look out for as he is tipped to start for the first time under Labbadia. The Pole has found the net twice in the last two matches from the bench, and has proved to be a threat to the defence when given his chance.
This fixture has been dominated by Borussia Dortmund who have not fell to a defeat since March 2017.
The reverse fixture in November saw Die Schwarzgelben edge a 2-1 win in the German capital despite the first-half dismissal of Mats Hummels. VAR came to the rescue for Dortmund that day as a goal from Davie Selke was ruled out for offside.
Where to watch on TV
BT Sport will be showing the tie, as they have with each of the Bundesliga fixtures since the restart. BT Sport 1 and BT Sport Ultimate have been allocated for this one, which kicks off at 17:30 BST.