Bayern Munich have confirmed that Holger Badstuber will be out for three months after fracturing his ankle in training.
The defender, who is known for his rotten injury luck, suffered the fracture during the final preparations for their game with FC Augsburg.
He was taken to hospital for a final diagnosis and surgery to repair the damage, in what is a huge blow to both player and club.
Bad luck Badstuber
This is the latest injury set-back for the 26-year-old centre-back, who has endured problem after problem that would make most players think twice about calling it quits.
However that is far from the thoughts of Badstuber, who has been nothing but positive on social media after the news was announced.
The problems started with a cruciate ligament tear back in December 2012, which kept him out of action for a staggering 532 days.
A torn tendon and a serious thigh muscle injury kept him out of large parts in 2014/15, and he only recovered from the latter set-back in November.
This fractured ankle will likely see him out until mid-May, meaning he'll miss the crucial part of Bayern's run in.
More defensive woes for Bayern
Badstuber's latest spell on the sidelines means he joins a the majority of the back-line already in the treatment room.
Jerome Boateng and Javi Martinez are out for extended periods of time, while Mehdi Banatia is still battling for fitness.
Against Augsburg, Bayern began with no recognised centre-backs - Serdar Tasci remained on the bench as he continues to miss out.
Perhaps the only positive is that Joshua Kimmich has been outstanding in everyone's absence, as well as the sturdy David Alaba beside him.
It looks likely that this will be the preferred partnership for Guardiola going forward, at least until he is happy that Benatia is back up to speed.