The Dons have won back to back games, after they previously went five without winning.
Despite being in 14th place, Russel Martin's side are one of the top scorers in the league with 52 goals, however, they've also conceded 51.
Meanwhile, the Brewers are the team to beat at the moment, they are one of England's most in-form teams, unbeaten in seven.
Jimmy Floyd Haselbaink has done a tremendous job of turning the clubs fortunes around.
There is no new injury concerns for Haselbaink, however Danny Rowe could well be a doubt for this fixture as he limped off 15 minutes in against Blackpool midweek. It was possibly just a precaution to bring Rowe off, as they wouldn't want to lose him for a lengthly amount of time.
Dons on the other hand, have a full squad to choose from, and have no new injuries or suspensions.
Burton Albion (4-2-3-1)
Garratt; Brayford, Carter, Bostwick, Hamer; Edwards, Mancienne; Smith, Powell, Akins; Hemmings.
MK Dons (3-4-1-2)
Fisher; O'Hora, Lewington, Darling; Laird, O'Riley, Surman, Sorinola; McEachran; Grigg, Jerome.
Ones to watch
Kane Hemmings - Burton Albion
It was his first treble for the Brewers, and he now has 13 goals this season.
He's physically strong and stands at 6'1, and has been one of the key figures in this Burton revival since the turn of the year, scoring some big goals.
Dean Lewington - MK Dons
Dean Lewington at 36 is the Dons' longest serving player, 18 years to be exact. He is set to make his 800th appearance for them this weekend.
He has been there through thick and thin for the Southerners, seeing promotions and relegation in his time at the club.
Lewington has played at both centre back and left back but most recently has found himself in a back three.
Just this week, he has signed a new contract with the Dons taking him into his 18th playing season.
When the sides met back in December, it ended in a 1-1 draw at Stadium MK, where a Scott Fraser penalty cancelled out an early Burton goal.
How to watch
Due to current restrictions in the UK, there will be no fans in attendance in Burton. However, it is available to watch on iFollow where passes can be purchased via club websites. The kick-off is at 15:00 GMT.