Visitors Atletico Madrid will aim to continue their winning ways and maintain third place in La Liga, with Sevilla hot on their tails - the two sides are only separated by goal difference, both boasting 66 points.
Despite winning their last match against Real Betis 1-0, with the only goal of the game coming from Diego Costa, Athletico battled with ten men for the best part of 33 minutes, as Mario Hermoso saw red in the 57' minute.
As for the hosts, Getafe are fresh off a 0-0 draw away to Alaves, Getafe will look to get back to winning ways in what is their penultimate game of La Liga's season - with a clash against Inter Milan in the Europa League on the horizon.
In a match which has got such a history of being a heated affair, the battle in the midfield will certainly be a ferocious one. Atletico's Thomas Partey has impressed in the middle of the park for some time now, with an average match rating of 7.16 (via WhoScored.com), Partey is vital to Atletico's set up. The midfielder breaks up the play and protects his back four with ease.
Getafe's Allan Nyom will be welcomed back to the side after serving his suspension and will look to go beyond the Atletico defense. Madrid's Renan Lodi will have to deal with the pace and strength of Nyom and aim to keep his cool. Nyom's penetrating runs could well frustrate Lodi, who will aim to stay on the pitch for the full 90 minutes this time round and avoid a red card.
Last time the two sides met, Atletico emerged the victors at the Wanda Metrapolitano with a goal from none other than Alvaro Morata proving to be the difference between the two sides back in August. Both sides played with ten men for long periods of the game, as Lodi and Jorge Molina Vidal saw red as the first half was concluding.
Atletico have won the last four encounters against their counterparts from Madrid, scoring six and conceding none across those encounters.
Getafe will be without both Xabier Etextia and Damian Suarez (suspended), with Peter Etebo also missing the match through injury.
Right back Nyom is expected to return to the side after completing his suspension.
Atletico will be without Mario Hermoso after the defender picked up a red card. Despite still recovering from a knock to the ankle, Jose Gimenez might well feature alongside Stefan Savic in the heart of the Atletico defense.
Kieran Tripper is also a doubt, after being taken on in Atletico's last match with stomach issues.
Getafe XI: Soria; Nyom, Dakonam, Cabaco, Olivera; Maksimovic, Arambarri, Timor; Jason, Mata, Cucurella (4-3-3).
Atletico XI: Oblak; Arias, Gimenez, Savic, Lodi; Saul, Thomas; Carrasco, Llorente, Koke; Costa (4-2-3-1).