The Tigers began life back in the EFL Championship with a resounding victory over Preston North End, but have dropped contests to Queens Park Rangers, Derby County and Fulham without scoring in any of those defeats.
Bournemouth have picked up eight points from their opening four games of the season with victories over Nottingham Forest and Birmingham City as well draws against West Bromwich Albion and Blackpool.
Hull will be without George Moncur as he serves the third of his three-match ban. George Honeyman is out as he recovers from ankle surgery and leading scorer Mallik Wilks is also sidelined with a calf problem.
Ryan Longman went off against Derby with a groin strain, but has returned to training and could feature while defender Alfie Jones missed the defeat to Fulham with his own groin problem, but is close to re-joining the Tigers.
Bournemouth will welcome back Jefferson Lerma after the Colombian international has finished serving his six-match ban. Right-back Jack Stacey is progressing in his recovery from a quad injury, but fellow defender Adam Smith is slower in his recovery.
Manager Scott Parker said Junior Stanislas will miss a few weeks with a hamstring issue and he should return following the international break. Central midfielder Lewis Cook (ACL) is also weeks away, but is back on the training ground.
Hull City: Ingram; Coyle, Bernard, Greaves, Elder; Docherty, Smallwood; Williams, Smith, Lewis-Potter; Magennis
AFC Bournemouth: Travers; Zemura, Kelly, Cahill, Mepham; Billing, Marcondes, Pearson; Anthony, Solanke, Brooks
Ones to watch
With Wilks out, Lewis-Potter will be asked to be Hull's main attacking threat. The talented, pacy midfielder score against Preston and set up the Tigers' second. He also found the back of the net against Wigan Athletic in the Carabao Cup.
He's been by far the Cherries' best player this season. His link-up play in the draw against Blackpool was precise and he nearly had a hat-trick. His movement also illustrates just how aware he is at all times on the pitch and will command Hull's attention at all times.
Having last met in the Premier League in the 2016-17 season, each team won at home. The Cherries ran riot with a brace from Stanislas in a 6-1 victory.
The Tigers were 3-1 winners after a pair of goals by Abel Hernandez cancelled out Stanislas' opener from the penalty spot. Tyrone Mings’ own goal ensured Hull got a third goal and the three points.
How to watch
There is no live streaming coverage. Audio commentary is available on iFollow Tigers for Hull fans and AFCBTV for Bournemouth fans. Kick-off is scheduled for 15:00 BST.