New York is coming off of a 2-1 victory over Orlando City in their last outing while Nashville is unbeaten on the season, having won two and drawn five of their seven matches this season.
New York will be without midfielder Cristian Casseres Jr. as he is away on international duty with Venezuela in the Copa America tournament. Dru Yearwood is likely to take his place. Youba Diarra, signed on loan from Red Bull Salzberg, may not feature after picking up a hamstring knock in the opening game of the season.
Center forward Daniel Rios had a minor setback as he continues to rehab from a groin injury that has kept him out for the entire season so far. Brian Anunga is also unavailable for selection with quad and knee issues. Walker Zimmerman, Randall Leal, Anibal Godoy and Alistair Johnston should all be available for Nashville as they return from international duty.
New York Red Bulls: Miguel; Edwards, Nealis, Reyes, Duncan; Yearwood, Davis; Clark, Amaya; Kilmala, Fabio
Nashville SC: Willis; Lovitz, Zimmerman, Romney, Johnston; McCarty, Godoy; Leal, Mukhtar, Muyl; Badji
Ones to watch
Fabio is second in the league with four assists and has excelled at both ends of the pitch, fitting in perfectly with the high-pressure system employed by coach Gerhard Struber.
Hany Mukhtar scored both of Nashville's goals in their 2-2 draw against Atlanta United last time out. He's the only player in franchise history to tally multiple goals in two or more MLS matches.
This is the first-ever meeting between New York and Nashville.
How to watch
The match will be shown nationally on ESPN+. In local markets, MSG Network will carry the game in New York while MyTV30 will broadcast the match in Nashville. Kick-off is scheduled for 8pm ET.