Sunderland's poor run of continued at the Stadium of Light this afternoon as they beaten 2-1 by Milton Keynes Dons.
Max Power gave The Black Cats the lead on 12 minutes, but were pegged back just four minutes later by Cameron Jerome's equaliser.
The away side were awarded a penalty when Power brought down Scott Fraser after trying to clear the ball away.
Fraser made no mistake from the spot, sending Remi Matthews the wrong way to seal the away side their first away league victory in 14 months.
Here are the most important responses that the Sunderland boss made to the media:
Not good enough in front of goal
Parkinson branded Sunderland's performance as 'unacceptable', and blamed missed chances for his team's defeat this afternoon.
"It's very frustrating, certainly the second goal right at the start of the second half, which cost straight from our kick-off.
"There were three errors leading to that, and the foul that led to the penalty was unacceptable.
"In terms of chances in and around the six-yard box, it is unacceptable that we haven't taken them - I think that's fair.
"You don't get gilt-edged moments like we got today, and like we have been getting, and not take them, and then expect to be at the top.
"We had four or five moments today in and around the six-yard area when we just needed a bit of composure to get us a goal, and it is unacceptable that we haven't taken those moments today."
Another disappointing afternoon for Will Grigg
Will Grigg missed a golden opportunity to tie the game, and Parkinson told the media that he knows that the £4 million-man will be kicking himself for his performance this afternoon.
"Will worked his socks off for the team, first of all.
"Last week he needed that game because he hadn't played for a while - there were a couple of times when he was going to play and he picked up little niggles.
"So physically he looked better this week than last week, but he knows - and he was the first one to hold his hands up in the dressing room - that those moments have got to be made to count."
MK Dons' penalty was 'soft'
Parkinson felt the penalty awarded to MK Dons was 'soft', which resulted in his side falling to defeat.
"To concede a penalty from our kick-off is very, very poor.
"It was a soft decision, there was contact right on the line, and I suppose in the light of what penalties are now given for then we can't have too many complaints."
Two humiliating home defeats in a row
Sunderland have been beaten in their last two home games, with the loss one prior to today's against MK Dons being a 1-0 defeat against League Two side Mansfield Town in the FA Cup.
Parkinson said that himself, the players and the staff are 'angry' at what has happened the last two times they have played at the Stadium of Light.
"We're all angry - no-one likes losing.
"We made changes for the Mansfield game, some were enforced, some weren't but they were players we wanted to give a breather.
"We felt that it was the right decision to rest players and try to get a result today but we haven't been able to do that.
"There was probably no team playing football in the 3pm kick-offs today who had as many clear-cut chances in and around the six-yard box as us.
"Those chances don't come ten or 12 times in a game, it's four or five moments, and you have to take them.
"We are creating good quality chances but we have missed far too many gilt-edged opportunities in this game, and in others."