The Royals' fine form has seen them rise to fourth in the Championship table, leaving them just four points off of an automatic place.
Meanwhile, the Potters are sat just outside of the play-offs in 10th position, four points off the play-offs,
Stoke are without ay left-backs, with Morgan Fox out injured and Rhys Norrington-Davies suspended. They are also without Tyrese Campbell who is out for the rest of the season.
Reading have a number of players coming back, with Felipe Araruna and George Puscas close to a return. Liam Moore is still some way away.
Gunn; Collins, Souttar, Chester, Smith, Thompson, Allen, Mikel, McClean, Brown, Fletcher.
Rafael; Holmes, Morrison, McIntyre, Richards, Laurent, Rinomhota, Meite, Swift, Ejaria, Joao.
Ones to watch
One of many young players to star for the Potters so far, a towering centre-back who has a great partnership with Nathan Collins and James Chester. He signed a new long-term deal with Stoke on Friday, and deservedly so. Expect him to be a big problem for Lucas Joao.
The Portuguese striker has been nothing short of sensational for the Royals so far this season, scoring 15 goals in what his most prolific season yet. He has height, strength, skill, flair, all the attributes needed for a complete striker.
The last time these two sides met was earlier in the season when Stoke inflicted Reading's third defeat in a row in the league back in November with a 0-3 win at the Madejski Stadium.
How to watch
This match will kick-off at 15:00 pm on Saturday, February 6, and is available to watch by purchasing an iFollow pass for £10.