The Millers come into this game on the back of a narrow 1-0 defeat away to league leaders Norwich City.
Meanwhile, the visitors picked up a vital three points in the battle for survival, with a solid 1-0 victory against out of form Blackburn Rovers.
Coming into the game, Rotherham sit in the relegation zone two points from safety but with two games in hand. After recent run of good form, Forest sit in 17th and now have a seven-point cushion over their opponents.
The Reds remain without midfield trio Sammy Ameobi, Samba Sow and Harry Arter with injuries preventing them from being involved at the New York Stadium.
Rotherham United (3-5-2):
Johansson; MacDonald, Robertson, Ikiekwe, Olosunde, Wing, Wiles, Barlaser, Giles, Crooks, Smith.
Nottingham Forest (4-2-3-1):
Samba, Christie, Figueiredo, Ribeiro, Cafu, Garner, Mighten, Krovinovic, Knockaert, Murray.
Ones to watch
Michael Smith - Rotherham United
The target man may not be the most clinical of strikers, but he does cause Championship defenders a lot of trouble. With seven goals and three assists, the 29-year-old is enjoying one of his most prolific seasons in recent times. His aerial ability is what will trouble the Forest defenders most so will need to be kept under wraps.
Alex Mighten - Nottingham Forest
Alex Mighten has had a rapid rise this season. Despite not turning 19 until April, the Reds academy graduate has made 16 appearances this season and his pace and athleticism have brought fresh life into the Forest forward line. The youngster has two goals to his name this season with the latest of his two strikes coming at the weekend.
The two sides last met at the City Ground back in October with the points shared in a 1-1 draw. Over the last five encounters, Forest have picked up two victories with Rotherham just the one coming in the last meeting at the New York Stadium. Out of the last 23 meetings between the sides, Forest have avoided defeat on 21 occasions.
Last time out...
How to watch
Due to the current national lockdown, no fans will be in attendance at the New York Stadium. This means the game is available on iFollow through Rotherham and Forest's respective club websites, with passes being priced at £10.
The game is also live on Sky Sports Football.
The game kicks off at 19:00 GMT on Tuesday 23 February 2021.