The Hatters will look to maintain their 10/10 start as they began the campaign last week with a 3-0 thumping at home against newly promoted Peterborough United. Goals from Elijah Adebayo, Harry Cornick and Fred Onyedinma helped ensure their sides season started off in winning ways.
However, The Baggies did not kick theirs off in style on Friday as they drew 2-2 away to Bournemouth in the season's opener. Equalisers from Dara O'Shea and Callum Robinson helped the newly relegated outfit prevent their campaign from starting with despair.
The hosts start their season as clear favourites to get automatic promotion back to the Premier League. The visitors however look to be a side that will be in and about the battle for the play-offs come the latter stages of the year.
The Baggies will expect their quality to see off any threat in this fixture but a very strong Luton side will fancy themselves to grab a win at The Hawthorns for the first time in 25 years.
Baggies boss Valerien Ismael has no injury concerns to his starting lineup for his first game at The Hawthorns as manager. Ismael has also revealed that experienced midfielder Robert Snodgrass is getting ever closer to returning to the match day squad after returning to full training. The manager believes his personality and experience will prove valuable throughout the campaign when he gets back to full fitness.
Luton manager Nathan Jones will still be without captain Sonny Bradley for the clubs first away trip of the season. Defender Reece Burke could be in contention to start at The Hawthorns, after playing 90 minutes in midweek against Stevenage.
Button; O'Shea, Bartley, Kipre; Townsend, Mowatt, Livermore, Furlong; Robinson, Ahearne-Grant, Phillips.
Sluga; Bell, Osho, Burke, Brea; Clark, Ruddock Mpanzu, Campbell; Onyedinma, Adebayo, Cornick.
Ones to watch
After opening his account for the season last Friday, Robinson will look to terrorize a weakened Luton defence. After a fantastic stint in the Premier League last season, the winger is bound to run rings around most teams he is up against. The former Sheffield United man is by far the Baggies' most dangerous player going forward.
Onyedinma had the perfect start to the Championship season last week against Peterborough, bagging a goal and two assists for Luton in his first competitive league fixture. The Nigerian will go to the midlands with full confidence he can replicate his stunning performance in the game prior.
These sides met three times in 19/20. Once in the league cup and twice in the Championship. West Brom came out winners in all three. The most recent fixture ended 2-0 to The Baggies in February 2020. A header from Semi Ajayi and own goal by Donervon Daniels helped Slaven Bilic's side cruise past Luton.
How to watch
If you're unable to be at The Hawthorns, the game is not being televised live on television in the UK, but is available to watch on the EFL's digital iFollow platform for those outside of the UK. Kick-off at 15:00 BST.