AFC Bournemouth look for a second straight win to start the season as the Cherries visit two-time defending Premier League champions Manchester City.
A convincing 2-0 victory over Aston Villa marked Bournemouth's return to the top flight with Jefferson Lerma and Kieffer Moore scoring either side of halftime.
City also opened up their latest title defense with a 2-0 win, defeating West Ham United on the back of a brace by Erling Haaland.
The Cherries will look to end an 11-match losing streak to the Citizens in all competitions, outscored 32-5 in that span.
Team news
Manchester City
Kalvin Phillips will be unavailable to make his debut for the Citizens with manager Pep Guardiola saying the midfielder is struggling with "niggles".
Cole Palmer is also out with a foot injury while defender Aymeric Laporte had knee surgery in the summer and is still sidelined.
AFC Bournemouth
The Cherries could welcome Marcos Senesi into the squad following the defender's move from Dutch side Feyenoord.
Goalkeeper Neto arrived from Barcelona and could be involved, although Mark Travers is expected to keep his starting spot.
Ryan Fredericks (calf) and Joe Rothwell (quad) are still a few weeks away from returning.
Likely lineups
Manchester City: Ederson; Cancelo, Aké, Dias, Walker; Gündogan, Rodri, De Bruyne; Grealish, Haaland, Foden
AFC Bournemouth: Travers; Kelly, Mepham, Lerma; Zemura, Billing, Cook, Smith; Solanke, Tavernier; Moore
Key players
Erling Haaland (Manchester City)
This is an obvious choice as the Norwegian scored both goals in the win over West Ham last week. Fast, strong and powerful, Haaland is also excellent with his feet and knows when to utilize his many talents.
City paid Borussia Dortmund €60 million for the 21-year old's services and if last week is any indication, he will be worth every penny.
Jefferson Lerma (AFC Bournemouth)
Normally in the midfield, Lerma was moved into the Bournemouth defense by manager Scott Parker in pre-season and played there against Villa last week.
The Colombian can move back to the midfield with his ability on the ball, leading the way in transitions and showing his overall versatility. Was superb in the Cherries opener.
Match details
Where is the match being played?
The match will be played at the Etihad Stadium.
What time is the match?
Kick-off is set for 15:00 BST.
How can I watch the match?
Due to local blackout rules, the match will not be shown on live television. Manchester City will have live audio coverage through their official app.