Cambridge United will look to make it four league wins in a row as they host Bolton Wanderers at the Abbey Stadium.
The U's put on yet another scintillating attacking display on Tuesday night as Paul Mullin's hattrick secured a 3-1 win over Port Vale and kept Mark Bonner's side at the top of the League Two table.
This weekend sees them face a Bolton side without a win in their last four in all competitions, with Ian Evatt's men salvaging a late 3-3 draw at Barrow on Tuesday.
Long-term absentee Liam O'Neil remains the only Cambridge player on the sidelines with U's boasting a clean bill of health ahead of this weekend's fixture.
However, head coach Bonner has hinted that there may be possible changes to the starting eleven, with multiple midweek fixtures to come over the next few weeks.
He said: “I think we’re good but we have to keep an eye on one or two.
“Hiram (Boateng) has played 65 to 70 minutes which is the longest time he has played since January so we need to just be careful with that.
“We need to keep our eye on one or two others that have played big minutes in lots of games."
The visitors look set to be boosted by the return of Nathan Delfouneso after the forward missed the draw at Barrow following the birth of his newborn son.
Midfielder Tom White could also be back in the squad after he returned to training this week, having not featured in first-team action since the defeat to Shrewsbury Town on October 8.
Mitov; Knoyle, Taylor, Darling, Iredale, Hannant, Digby, May, Dunk, Hoolahan, Mullin
Crellin; Kioso, Santos, Delaney, Gordon, Brockbank, Comley, Sarcevic, Crawford, Delfouneso, Doyle
One to watch - Paul Mullin
There have been few better than Mullin so far this season, with the U's forward already registering ten goals - seven of which have come in his last three games.
After grabbing a hattrick in the win over Port Vale on Tuesday night, the 25-year-old looks set to cause problems for the Wanderers' defence.
Despite coming up against one of this season's early strugglers, Cambridge boss Bonner stressed that his side will still have to work hard to secure a result.
He said: "We'll have to work hard and accept that sometimes we won't have the ball but we also have to put our stamp on the game.
"We need to be ruthless in the periods where we're on top, which we have been, and we'll need to defend well and resolutely.
"That is the game all the time, putting every part together and trying to get through the difficult bits and come out on top."
Evatt acknowledged the need for a positive performance from his side, especially coming up against the form team in the division.
And with the pressure firmly on the hosts as favourites, the Wanderers manager believes it can be the perfect opportunity to improve on past mistakes.
He said: “We need to put it together, we know that and we are working hard to do that.
"We can see what’s wrong, they can see what’s wrong but they’ve got to go out there and do it and we’ve got a great opportunity now to go to the league leaders at present and get a result and if we play like we do and have done in spells, we’ll give them a good game.”
You'd have to go back to April 1991 to find the last league meeting between these two sides, where Cambridge came out 2-1 winners over at the Abbey Stadium.
The U's would go on to be promoted as champions that season from the old Football League Division Three, whereas Bolton finished 4th.
How to watch
The game is available on either club's iFollow streaming service, with match passes priced at £10.