The Tykes have been in strong form recently and are unbeaten in their last six league games, winning their last three in succession.
Visitors Stoke have recorded back-to-back home wins without conceding a goal after a barren spell of nine Championship games without a win.
Ismael could hand a start to January signing Carlton Morris after the forward came off the bench to score in his last two matches.
The Tykes manager may also bring Herbie Kane and Toby Sibbick into his starting eleven to maintain freshness in the squad.
Michael O'Neill has no new injury concerns in his team and could name an unchanged side from their last game.
Sam Clucas is pushing for a start after the midfielder impressed and provided an assist in just 15 minutes as a substitute against Luton.
Josh Tymon will face stiff competition from James McClean and Josh Clarke to start at Oakwell after both impressed in their short cameos off the bench.
Walton, Andersen, Helik, Sibbick, Brittain, Palmer, Mowatt, Styles, Morris, Woodrow, Chaplin.
Gunn, Smith, Batth, Souttar, Norrington-Davies, Allen, Thompson, Brown, Powell, Tymon, Fletcher.
Ones to watch
After a slow start at Oakwell since joining from Norwich in January, Morris has found his feet in South Yorkshire, hitting three goals in his last three games.
As top goal scorer, Cauley Woodrow has hit a barren spell; Morris is becoming increasingly important for The Tykes.
Nick Powell seems to have hit his stride in the Potteries and is proving himself as one of the leagues most dangerous forwards.
The former Manchester United man is a player in form at the moment, scoring five goals in his last six games, including two last time out against Luton.
In the absence of Stoke talisman Tyrese Campbell, Powell has become a key component in O'Neill's side.
This is a fixture that has provided plenty of goals in the last couple of seasons, with a total of 20 goals in the last four meetings.
The last time the sides met was a 2-2 draw in late October, which saw four goals in the first 49 minutes and a red card for Stoke teenager Nathan Collins.
The Potters won on their last visit to Oakwell, which was manager Michael O'Neill's first game in charge and ended 4-2 to the visitors, including a sublime long-distance strike by Sam Clucas.
Barnsley recorded their last win against Stoke back in 2007 when a first-half strike from Istvan Ferenczi was the difference between the sides.
Before that, you would have to go way back to 1996 to find the last time The Tykes defeated The Potters.
Due to the ongoing national lockdown, no fans will be in attendance for the fixture, the only way to watch the action will be to purchase a stream from one of the clubs streaming platforms.
Barnsley use iFollow, with streaming information available here.
Stoke City's streaming information can be found here.