Luton Town were heavily beaten in their last game against league leaders Norwich City at Carrow Road by three goals to nil.
Whereas Swansea City played in midweek, where they travelled to Ewood Park and came away with a draw against Blackburn Rovers. Another Andre Ayew penalty salvaged the Swans a point.
In the reverse fixture between the two sides, Swansea came away with a comfortable 2-0 win, after Conor Roberts' goal after two minutes set them on their way. Ayew grabbed a late goal to seal all three points.
Luton boss Nathan Jones made five changes for this fixture.
Elijah Adebayo led the line with James Collins on the bench, whilst there was a start for James Bree at right-back for the first time since their defeat against Stoke City.
Pelly-Ruddock Mpanzu was alongside Ryan Tunnicliffe and Kiernan Dewsbury-Hall in midfield, and Harry Cornick was the fifth change.
Swansea head coach Steve Cooper also made five changes for the affair.
Ryan Bennett, Joel Latibeaudiere, Ryan Manning, Korey Smith and Yan Dhanda were the changes brought into the side.
Marc Guehi missed out through injury, while Ben Cabango, Jake Bidwell, Jay Fulton and Jamal Lowe dropped to the bench.
Swansea took a lead on three minutes after countering from a Luton opportunity. Dhanda found Conor Hourihane free in the area to bury it past Simon Sluga.
Luton found the net with defender Dan Potts heading past Freddie Woodman, but the linesman made the right call to call it offside.
The Hatters pushed and pushed for an equaliser, but it wasn't their day as Swansea came away with the three points.
Story of the match
A glorious chance came on two minutes for Luton as the ball came in from a corner, flicked on by Adebayo, Matt Grimes tried to clear his lines, but the ball fell to Kal Naismith, who scuffed his shot to fall into the hands of Woodman.
Woodman threw the ball out and a long ball over the top give Dhanda all the time in the world to attack down the left. He found Hourihane free inside the area to guide it home to give the swans the lead.
Luton were holding all the attacking threat inside the first ten minutes, and Jordan Clark came ever so close with a give and go with Tunnicliffe for him to bend his effort inches wide.
Minutes later, Luton had the ball in the net, unfortunately for The Hatters, the linesman had his flag up. A searching ball from Cornick on the right-wing, saw Potts leap above the Swansea defence to head the ball into the net. A correct decision from the linesman, as potts strayed offside.
Adebayo was doing everything to put Woodman under pressure, and the Swans goalkeeper nearly gifted Luton an equaliser. A weak kick fell to Mpanzu around 40 yards out, his dipping effort was nearly perfect, but Woodman was able to parry the ball out for a corner.
We had an eight-minute stoppage before half time due to Potts colliding with Hourihane. In the end, he was taking off on a stretcher with Martin Cranie replacing him.
There were shouts for a penalty in added time with the ball appearing to hit Ryan Manning's hand after it was flicked into the area, referee Darren Bond wasn't interested as the Luton players appealed. There seemed to be a push on Ayew anyway.
The Hatters pretty much dominated the first-half and they'll be wondering how they didn't find the net in the first 45.
It was the same result at the start of the second-half as Luton came out all guns blazing. Adebayo with a whipping low cross in the area, Cornick was inches away from connecting with it.
A sloppy free-kick from Naismith was gifted straight to Grimes, as he found Hourihane on the edge of the area, The Irishman opted to shoot early and he dragged his effort straight at Sluga.
Luton came so close, yet again, just after the 60th minute. Dewsbury-Hall found Cornick on the right who crossed the ball perfectly to the head of Clark, his header was miss-timed and it grazed his head instead of getting power on it. Another wonderful opportunity for The Hatters went begging.
Another penalty call screamed out from Luton as Adebayo fell down, but Latibeaudiere seemed to win the ball, another correct decision from the officials.
A half-chance came in the last minute of additional time, a whipped cross into the area, landed to Adebayo, but his header was too tame and fell easily into the hand's of Woodman, the story of Luton's day.
It was a second half of little chances, as Swansea came out to play more a little, but overall, a quiet day up top for Ayew.
Nathan Jones will be gutted that his side hasn't come away with at least one point never mind three points.
In the end, not the best Swansea performance, but it's the three points that matter, as they now sit in second before the other game's kick-off.
Luton sits in 16th and will stay there this weekend, as Nottingham Forest sit closest to them, four points behind.
Even though they lost the game, it would have been an almost perfect display from The Hatters, if they could've found the net. In the first half, they were at the Swansea defence from the get-go.
Adebayo ran his socks off but struggled to test the keeper. It was possibly the wrong decision to bench their top-scorer Collins because he could've had a handful today.
It wasn't the most impressive display from the promotion challengers, with minimal chances created throughout the game.
When you're a top team in the league it proves you sometimes only need to take that one chance to win the game, as Swansea defended well to stop the Luton attacks.
Man of the match
It's hard to pick a man of the match from a losing side, but in this one, it's a must. Dewsbury-Hall ran the midfield and created all the play for Luton, it was down to his attackers not finding the net which let the side down.
All the Swansea players were too quiet, the likes of Ryan Bennett and Latibeaudiere defended well, but no attacker deserved the man of the match award.