Despite reaching two cup finals last term, and finishing eighth in the Premier League, the Reds will be hoping to push on further in the German's first full season.
After only registering two losses during their pre-season, optimism is high for Klopp’s first full season in charge at Anfield. Arsenal, as always, are expected to do well in the league, but with a lack of signings could fall below fellow rivals.
The German has put his mark on his side by making multiple signings, with Sadio Mané being the marquee man at £30 million. Klopp is expected to hand competitive debuts to many of his new signings tomorrow.
Arsene Wenger has a defensive crisis and is missing key centre-backs Laurent Koscielny, Per Mertesacker and Gabriel.
As a result, new signing Rob Holding is expected to make his debut, in an unorthodox centre-back partnership with Calum Chambers.
£32 million summer signing, Granit Xhaka is also set to make his competitive debut for Arsenal, whilst Danny Welbeck and Olivier Giroud miss the opening game through injury.
For the Reds, they are likely to be without Daniel Sturridge and James Milner, but new men Mane, Joel Matip, Ragnar Klavan and Georginio Wijnaldum could all make their debuts.
Goalkeeper Simon Mignolet is set to start in goal for Liverpool, due to new 'keeper Loris Karius breaking his hand during a pre-season game.
Arsenal fans have been left frustrated this summer with a lack of signings.
Granit Xhaka was signed early in the window, treating fans to a bit of rare early business, but since then no big name signings have come in.
Many expected a new striker to come in but, with Jamie Vardy opting the stay at Leicester City, the Gunners have failed to sign another forward and bolstering their attack.
However, Wenger’s men enjoyed an undefeated pre-season, with their best result coming against Manchester City, where they won 3-2.
The Gunners have a very impressive record against the Reds, having only lost once in their last 10 meetings between the two sides in the league and cups.
Liverpool have only beaten Arsenal once in their last 20 away trips, coming in 2011.
League matches between the two sides have seen 16 goals being scored in the 90th minute or later, with the Reds recording nine of those.