Wycombe would have taken spirit from their valiant FA Cup run, which saw them hold Tottenham Hotspur level at 1-1 until the 85th minute, and will need that sort of determination if they are to take anything away from this fixture.
The Bees will be without Swedish centre-back Pontus Jansson and midfielder Shandon Baptiste, who are still both out injured. While former star Saïd Benrahma has also made his loan move to West Ham United a permanent deal, though this always was the expectation.
Anthony Stewart looks set to be the only absentee from Gareth Ainsworth's otherwise unhampered squad.
Raya; Dalsgaard, Pinnock, Sorensen, Henry; Dasilva, Janelt, Jensen; Mbeumo, Toney, Canos.
Wycombe: Allsop; McCarthy, Grimmer, Knight, Jacobson; Bloomfield, Adeniran, Wheeler; Muskwe, Ikpeazu, Onyedinma.
Ones to watch
Sergi Canos has enjoyed being a more integral part of the Bees attack this term, and already has more league appearances than he managed in the entirety of last season. With star striker Ivan Toney yet to score in 2021, Canos could be the man to fire Brentford to victory.
With the bees expected to dominate this one from the off, Ryan Allsop may be a very busy man. This was certainly the case against Tottenham in the FA Cup, where Allsop made a number of good saves which should give him confidence.
Brentford are unbeaten in their last five meetings with Wycombe – a stretch that goes back all the way to 2010 and drops down to League One. However, the two played out a 0-0 draw when they met earlier on this season.
How to watch
This match will kick-off at 15:00 pm on Saturday, January 30, and will be available to watch on iFollow.