The Foxes were held to a 0-0 draw in the first leg of their round of 32 tie. The Czech First League leaders were tough to breakdown and the Champions League chasing Leicester had a tough time trying to find the back of the net.
Physical presence needed
With the pure power that Slavia Prague displayed over in the Czech capital last week, it would be wise for Leicester to be stronger from the off.
The East Midlands side didn't get much in the first leg from the officials, hence the need for more aggression in the middle of the park.
Hamza Choudhury was brought on in the final quarter to combat the aggression of the Czech side. The City academy graduate is often known for his old school style of playing, consistently being strong in the tackle.
Choudhury has been consistent recently, maturing on the pitch in recent months after being criticised by fans as a bit of a 'hot head'. Brendan Rodgers could potentially call on the 23-year-old to come into the starting lineup.
Maddison void to fill?
With James Maddison being ruled out of this huge tie with a hip injury, hopefully it will only be precautionary and the problem won't keep him on the sideline for long, much like it did last season where the 24-year-old was out of action for a while.
This leaves many wondering what Rodgers will do for the match and who he will pick. With Dennis Praet and Ayoze Perez also injured, aswell as Kelechi Iheanacho being suspended, it doesn't leave the Northern Irishman with many options.
All being considered, the lack of a creative '10' to choose from, this opens up the opportunity for Cengiz Ünder to play in that spot. Ünder, on loan from AS Roma hasn't had a consistent run in the team this season, however, it has been hard to considering the good form of Leicester's attackers. The Turkish international could be called up on as he has good feet, he is quick, and has shown he has the ability to pass.
On the other hand, the Leicester boss could also change the formation completely, playing a three or a five at the back with wingbacks, which would take away the number 10 position in behind Jamie Vardy.
Prague's tricky style of play
With it set to be a cagey affair and high in tension, there's no room for error as one goal can settle the contest.
Having not conceded a goal in Prague, the Czech side will certainly play knowing they have the advantage with the away goal rule set to come into play. Leicester simply cannot afford to concede, and must try and get the first goal.
It's going to be tough, considering Slavia Prague have one of the best defence's in European football.
Jindřich Trpišovský sets his side up to defend at the back in a low block, to then win the ball back and counter attack. It's proved to be effective both in the Czech First League and also in the Europa League.