In a game of not many clear cut chances, when called up on both goalkeepers did a terrific job at avoiding conceding.
Surprisingly, Brendan Rodgers only made one change to the side that beat Liverpool in dramatic fashion last Saturday. However, there wasn't so much the Northern Irishman could have done considering the away sides lengthy injury list.
It's all to play for in the second leg next week when Prague travel to Leicester in hope of nicking that vital away goal to go on and win.
Story of the game
Chances for both sides in the early stages
The hosts started well and were attacking the Leicester defence with intent, winning a couple of early corner balls. The away side's defence was tested, however multiple blocks prevented any real danger.
The Foxes also had the chance to score at around the quarter of an hour mark. Harvey Barnes drove with the ball but with pressure from the Prague defenders, the Leicester academy graduate couldn't squeeze the ball past the oncoming Ondřej Kolář.
Just a few moments late, Barnes was free at the back post. However, his lacklustre shot failed to hit the target.
Leicester penalty shout
The East Midlands side settled well after some early defensive work and worked their way coolly into the game.
Barnes was causing problems once again as the 23-year-old broke free following a dangerous James Maddison free-kick across goal. He then collided with a Prague defender and there was claims for a penalty but nothing was given in the end.
Prague applying pressure
The hosts came out looking very strong in the second half - the Fortuna Liga leaders pressuring the Leicester defence in the first 15 minutes after the break.
Jindřich Tripišovský's side attacked the Foxes and forced Kasper Schmeichel into a couple of saves.
With Leicester not being able to get out of their own half, Rodgers made two attacking changes with Kelechi Iheanacho and Cengiz Under coming on to replace Jamie Vardy and Marc Albrighton in hope his team could find a winner.
With a game that ended very intense, either side could not break the deadlock in a game of two halves really.
Prague were on top for much of the second half, giving them great confidence going into the second leg over in England. Leicester do not hit blank often, so the hosts did an excellent job in keeping the likes of Barnes and Vardy quiet.
Luke Thomas impresses again
Luke Thomas, who broke into the squad in the later stages of last season, has enjoyed a fruitful spell in the Europa League for the Foxes this season.
The youngster had a terrific game at left back and did well to defend his side with the ever so tricky Abdallah Sima attacking the right wing.
Thomas, the 19-year-old has played a key part in Leicester's successful Europa League campaign so far, and will probably keep his place for next week's second leg.
Vardy and Leicester struggle to create
In a game which really both sides were solid defensively and didn't provide many clear cut chances, it was a game where Jamie Vardy struggled and ultimately was isolated.
The Slavia Prague defence proved why they are the reason their side have gone unbeaten over in the league. They stuck tight to Leicester's attackers and were physical, not allowing much past them.
Vardy touched the ball no more than 15 times before he was dragged after just over an hour. However, the away side couldn't play to their talisman's strengths - sitting deep, not allowing the killer through pass to be played.
All to play for in the second leg
This time next week, the Czech capital side travel to the Midlands in the second leg in arguably Leicester's most important match of the season.
However, the away side have the advantage with the away goal rule in place in European ties.
Unfortunately with the travelling Foxes shooting blank in the away fixture, Prague will only need the one away goal to go through, so Leicester must score goals in the second leg.
Despite the away goal rule etc. Leicester will surely be favourites when they welcome Prague to the King Power next time out.