The Bantams have a new look upon their squad heading into the new season, with nine new faces through the door and the recent appointment of promotion winner Derek Adams, who departed Morecambe despite helping the Shrimps reach League One.
Matt Taylor's Grecians are going through a similar change, with ten new additions in the summer and the exit of club captain Jake Taylor, Exeter will be looking to build on last season and this campaign to reach the play-offs.
The Grecians have lost fifteen members of last seasons squad, including key players such as Randell Williams and Joel Randall, who joined Championship sides Hull Cityand Peterborough United respectively.
Taylor has recruited cleverly however, brining in the likes of Josh Coley, Sam Nombe and Cameron Dawson to implement a fresh impetus of youth into the first team.
Adams has also seen a rebuild throughout his squad, with nine players leaving the squad and nine coming in, including promotion winner Yann Songo'o, former loanee Andy Cook and Scunthorpe United wingers Alex Gilliead and Abo Eisa.
However, the Bantams will be without Songo'o (knee) and new signing Caolan Lavery, as Adams feels the former Sheffield United striker isn't ready to be involved in the squad. Elliot Watt may also be at risk, having only recently recovered from injury.
Exeter City: Dawson; Caprice, Ray, Grounds, Rowe, Brown, Collins, Dieng, Nombe, Seymour, Jay.
Bradford City: O'Donnell; Threlkeld, O'Connor, Canavan, Ridehalgh, Watt, Sutton, Vernam, Cooke, Eisa, Cook.
Ones to watch
An academy graduate and a key member of the Grecians squad, it's going to be a big season for Matt Jay.
The 25-year old nabbed himself 18 goals last campaign and a place in the Sky Bet League Two team of the season, but was also elected as the new club captain following the departure of Taylor.
Whilst it's unknown so far which formation Taylor will favour, Jay is an almost guaranteed starter in a strong Exeter squad and can play anywhere from central midfield to as a lone striker.
An integral part of the Bradford team, Callum Cooke is the sort of player that every team needs, acting as the anchor between midfield and attack.
Cooke played his first season in claret and amber in a deeper role, but under Mark Trueman and Conor Sellars last season, the midfielder ventured into an attacking midfield role, being a pivotal player in a 4-2-3-1 formation.
With the permanent addition of Cook and the arrival of a number of wingers, Cooke has more to work with this campaign and could be crucial in the outcome of Bradford's season.
Referee: Sam Allison
Assistant referee: Simon Shaw
Assistant referee: Mark Derrien
Fourth official: Alex James
The Bantams have only managed to defeat Exeter once ever, and that wasn't the case last season. Exeter managed to end a fantastic run of form which Trueman and Sellars had begun, as goals from Pierce Sweeney, Ryan Bowman and Jay cancelled out Charles Vernam and Ollie Crankshaw's first half strikes.
How to watch
The game will not be available to stream via iFollow this season for those in the UK, with Saturday fixtures kicking off at 15:00 BST no longer permitted. Tickets are still available for home and away fans.