The Foxes currently sit third in the table following their 1-1 draw against Everton at Goodison Park on Wednesday night and could go top of the league if Manchester City and Manchester United lose their games.
Leeds are currently sitting in 12th position in the league and are coming to the East Midlands on the back of beating Newcastle United 2-1 at St James Park.
Brendan Rodgers has confirmed he will be without striker Jamie Vardy and midfielder Wilfred Ndidi for the visit of Leeds.
Vardy had an operation on a minor hernia injury a week ago which left him out of the FA Cup tie against Brentford and the midweek game against Everton.
Ndidi had to be substituted in the first half against Everton as he had a minor hamstring tear. He is expected to be out for a week to 10 days. Wes Morgan and Dennis Praet are the only long-term injuries.
Marcelo Bielsa will be without Diego Llorente who went off inured with a hamstring injury against Newcastle and is expected to be out for a number of weeks.
Leicester XI: Schmeichel; Castagne, Fofana, Evans, Justin; Mendy, Tielemans; Albrighton, Maddison, Barnes; Perez.
Leeds XI: Meslier; Alioski, Cooper, Struijk, Ayling; Phillips; Raphinha, Dallas, Rodrigo, Harrison; Bamford.
The two teams last met at the beginning of December as the Foxes travelled to Elland Road in their first top-flight meeting since 2004.
The visitors got off to a flying start taking the lead after just three minutes, as a classic Leicester counterattack led to Jamie Vardy taking the ball past keeper Illan Meslier before playing it across goal to Harvey Barnes who slotted the ball into an empty net.
The Foxes doubled their lead after 21 minutes, as a ball in from Marc Albrighton was met by Vardy who forced a good save from Meslier, but Youri Tielemans reacted quickest to fire home the rebound.
Leeds got one back just after the restart as a ball in from Stuart Dallas surprisingly found its way into the back of the net as no one managed to get a head onto the cross taking Kasper Schmeichel by surprise.
Leicester got their third and Vardy got his first on 76 minutes, as James Maddison who had come off the bench produced a lovely through ball to fellow substitute Cengiz Under who then played the ball across the box for Vardy to fire into the empty net.
The rout was complete in stoppage time after Maddison was taken down foolishly in the box by Mateusz Klich, after originally not being given, VAR pulled it back and the Foxes were awarded a penalty.
With Vardy no longer being on the pitch the responsibility fell to Tielemans and the Belgian international placed it beautifully into the top left corner to get his second and seal all three points for the Foxes.
Ones to Watch
The Belgian international has been crucial to Leicester’s success this season, playing a vital role in Rodgers’ midfield.
It was the 23-year-old who got the equaliser against Everton and his passing and tempo dictated Leicester’s play in the game.
The midfielder has contributed to with a number of goals and assists this season and with Vardy on the sidelines, Leicester will need all the goals and assists they can get their hands on.
If Tielemans can put in another man of the match performance, Leicester could be on their way to another three points.
The Brazilian winger who signed for Leeds from French side Rennes in the summer has been a pivotal player in Leeds first season back in the top-flight.
He helped himself a goal and an assist in the away win against Newcastle ending a run of three games in all competitions without a win for Leeds.
If the Brazilian can put in another performance like the one against Newcastle, it could make for a very exciting game.
Speaking to the media about the test of missing Jamie Vardy, Brendan Rodgers said: "It’s the same test we’ve had all season when we’ve had players missing, Jamie is a top-class player, so is Wilf, but we’ve managed to get good results consistently over the season.
He continued: "As a coach or a manager, you have to find a way to get results and, very importantly for us, [maintain] the performance level.”
Marcelo Bielsa spoke highly of Leicester’s performance in the game against Everton.
The Argentine said: “In their game against Everton, they were the protagonists throughout. They had a style where they circulated the ball very quickly and a marked offensive style. They play to try and attack, and to position themselves in the opposition half. I think what stands out the most is the way they combine and elaborate to attack, that’s the most dangerous thing about them.”
How to Watch
The fixture is available to watch as part Sky Sports Super Sunday fixture list. Coverage starts on Sky Sports Premier League at 1pm with a kick-off time of 2pm.
Alternatively, you can watch live text updates on the VAVEL website and Leicester VAVEL Twitter page.