The Rams are fully healthy for this game with Aaron Donald practicing on Friday, his knee injury declared not serious. Wide receiver De'Sean Jackson was the other notable on the weekly injury report, but he is also active.
The Giants are not as fortunate as running back Saquon Barkley (ankle) and wide receiver Kenny Golladay (knee) both out. Fellow wide receivers Darius Slayton (hamstring) and Kadarius Toney (ankle) as well as offensive tackle Andrew Thomas (foot) are questionable.
Players to watch
Aaron Donald (Los Angeles)
The best defensive player in the NFL, the 30-year old has three sacks through the Rams first five games and shows no signs of slowing down. He's registered 88.5 sacks in his career and looks to be on his way to being one of the greatest defensive players of all-time.
Daniel Jones (New York Giants)
With the Giants missing several skill players for today's game, it's imperative that the third-year quarterback continue on the trend he's been on so far this year, throwing for 1,262 yards and four touchdowns, developing into the signal-caller New York thought they were drafting in 2019.
Los Angeles has won the last two meetings against New York, having outscored the Giants 68-26 in that stretch. They met last year at SoFi Stadium with the Rams coming out on top 17-9.
The last meeting at MetLife was a 51-17 drubbing by Los Angeles with coach Sean McVay in his first year.
FOX will be the national TV broadcaster for this game with Adam Amin as the play-by-play announcer and Mark Schlereth handling the analyst duties. Kickoff is set for 1pm Eastern time.