Charlotte were crushed 5-0 by league leaders LAFC last time out, their second consecutive loss as they are 11th in the East, four points out of a playoff spot.
Nick Cushing will be without the services of midfielder Keaton Parks and defender Alex Callens as both are nursing lower body injuries.
Midfielders Tayvon Gray and Gabriel Pereira are questionable with lower body injuries, but both should start if they are determined to be fit.
Vinicius Mello and Adam Armour continue to recover after undergoing left foot and left knee surgery, respectively.
Kerwin Vergas is questionable with a knee issue.
NYCFC: Johnson; Amundsen, Chanot, Martins, Acevedo; Morales, Moralez; Andrade, Rodriguez, Magno; Héber
Charlotte FC: Kahlina; Mora, Sobocinski, Walkes, Afful; Bronico, Bender, McNeill; Reyna, Swiderski, Józwiak
Ones to watch
Talles Magno (NYCFC)
He scored against Miami, bringing his total to six to go along with eight assists. With Valentin Castellanos on loan until next July, the dynamic young Brazilian will be the key player in the Boys In Blue attack.
Karol Swiderski (Charlotte FC)
The club's first-ever Designated Player has scored seven times and is developing a good partnership with Andre Shinyashiki in the heart of the Charlotte attack. The Pole is not just a scorer, but a complete forward.
This is the first-ever matchup between NYCFC and Charlotte.
Kickoff is set for 8pm Eastern time.