Scunthorpe boss Keith Hill has no fresh injury concerns ahead of the game aside from Sam Burns whose fitness will be assessed ahead of the game on Tuesday.
As for Jon Brady's Northampton, Jack Sowerby is a doubt after being substituted in their win over Colchester at the weekend while Shaun McWilliams is suspended and Chanka Zimba, Idris Kanu and Sid Nelson are all out.
Scunthorpe United: Watson, Millen, O'Malley, Delaney, Onariase, Pyke, Rowe, Feeney, Hackney, Nuttall, Grant.
Northampton Town: Roberts, McGowan, Horsfall, Magloire, Guthrie, Koiki, Pollock, Lewis, Pinnock, Appere, Hoskins.
Ones to watch
It's difficult to make a case for a danger man from the Iron with their joint top scorers, Myles Hippolyte and Ryan Loft, only on four goals this season.
January signing Joe Nuttall will be out to prove a point for Scunthorpe on Tuesday against one of his former sides Northampton.
Nuttall joined the Cobblers on loan last season but only appeared once and struggled to help the Cobblers survive relegation from League One.
The forward has made four appearances for the Iron this season and will be keen to get off the mark come Tuesday.
Northampton's main creative spark this season has without doubt been Mitch Pinnock.
Pinnock provided his eleventh assist of the season at the weekend when his corner was headed in by Fraser Horsfall to send the Cobblers on their way to a 3-0 win over Colchester.
The Cobblers have been League Two's set-piece specialists this season which Pinnock has been at the heart of.
However, Cobblers fans will also be delighted that their side also scored two from open play at the weekend, something that hadn't happened since their draw with Forest Green Rovers in mid-January.
The two sides have met 68 times previously and Scunthorpe will take a much-needed confidence boost into the game as they have the edge when it comes to their record against Northampton.
The Iron have 26 wins with 19 draws and 23 wins for Northampton.
Northampton won the most recent encounter back in September when they were 2-0 winners at Sixfields.
Where to watch
While the game is not being broadcast live on TV, both sets of supporters can watch the game live via their club iFollow service.