The Minstermen fell at home to fellow play-off challengers Boston United, ending their run of thirteen unbeaten. A Danny Elliot strike in the first half was enough to send the Pilgrims back to Lincolnshire happy.
Bottom of the league Farsley Celtic continued Leamington's torrid away form on a night where the Brakes saw multiple injuries strike, with the Celt Army winning 1-0.
Saturday's visitors were hit on Tuesday night, losing Kelsey Mooney after just eleven minutes. After a battle with a defender, Mooney looked to sustain a knee injury and was stretchered off. Steph Morley was unable to continue at half time at The Citadel and was also replaced. Top scorer Dan Turner was not included in the squad after suffering a hamstring injury.
There were some transfer movements to report on on Tuesday, with the loan deal of Callum Hawkins being extended. Fellow Burton Albion youngster Charlie Williams checked in with the Warwickshire side, also joining on loan until the end of the season. Connor Taylor was recalled from his dual-registration deal at Bromsgrove Sporting and came off the bench in midweek.
New City signing Maziar Kouhyar may not be available. The attacking midfielder joined from Hereford but is currently on international duty with Afghanistan and therefore has been unable to make his debut. Clayton Donaldson was not in the squad against Boston, manager John Askey confirming he had received a knock last Saturday.
York City: Jameson, Duckworth, Kouogun, Brown, Barrow, Wright, McLaughlin, Hancox, Dyson, John-Lewis, McKay
Leamington: Hawkins, Meredith, Morley, Clarke, Mace, Lane, Williams, Walker, Parker, Edwards, Kelly-Evans
Ones to watch
Well travelled striker Lenell John-Lewis has been leading the City line this season. After an illustrious EFL career spending time at clubs such as Bury, Grimsby Town and Shrewsbury Town, the Shop now plys his trade in the National League North.
With the visitors being suddenly struck by injury they will need a leader, and no doubt will look to skipper Jack Edwards. Bar a little spell at Solihull Moors, the attacking midfielder has nearly spent eight years at Your Co-op Community Stadium and is now Leamington's captain. Edwards has been out with neurological problems himself this season, but on his return after two and a half months out scored the winner against Blyth Spartans to end Leamington's winless run.
Leamington took all three points in comfortable style at Your Co-op Community Stadium back in November. Goals from Dan Turner and Kelsey Mooney fired the Brakes up to fourth in the table.
What the managers have said
Speaking to York's media team after their midweek loss, John Askey called the weekend's game "an opportunity to push on", noting that his Minstermen "can't dwell on (the defeat to Boston) too much, and we've got to learn from it."
Paul Holleran, who recently celebrated his 600th game in charge at Leamington, was disappointed after their game on Tuesday and told the club website that he is "bamboozled by the fixture lists in the division. We've ended up with more injuries tonight but we'll have to assess where we are now and we'll go again on Saturday."
John Askey has revitalised the Minstermen ever since taking the hotseat from Steve Watson, but will face his first real challenge since losing in aiming to avoid consecutive defeats after his side's 13 game unbeaten run. The Brakes are not prolific on the road though, and their away record this season has only seen one win.
Leamington boast the best defence outside of the play-off places and will be looking to continue their good defensive record against a York side who have scored 27 goals in their 17 home games this season.
City fans have made note of how teams approach playing at the LNER Community Stadium - talking of 'parking the bus', but Leamington have a good record against the Minstermen, having only lost once in the Chocolate City - and their last two home games ending with wins.
How to watch
As usual, this fixture will not be televised. Commentary will be available from BBC Radio York and coverage will be available from both clubs' social media accounts.
Kick off at the LNER Community Stadium is 3pm