The two teams find themselves in the bottom half of the table after average starts to the season. Both sides will be hoping to get another three points on Tuesday to help propel themselves further up the table and away from the bottom three.
Sheffield United have no new fresh injury concerns, with Oli McBurnie still out after testing positive for COVID-19.
Southwood; Holmes, Moore, Dann, Rahman, Drinkwater, Laurent, Yiadom, Swift, Ejaria, Puscas.
Foderingham; Basham, Egan, Davies, Bogle, Norwood, Fleck, Stevens, Gibbs-White, Sharp, Brewster.
Ones to watch
The six-foot-four striker made an impact coming off the bench on Saturday, with his sheer physique playing a huge part in Reading getting back into the game on Saturday. Expect him to make the same sort of impact in this game, too.
The veteran striker has been leading from the front this season for the Blades, with the striker racking up more assists for his side than actual goals so far this season. He is playing one of his former clubs tomorrow and will be hoping to get on the scoresheet.
The last time these two sides met was back in March 2020, when the two sides faced each other in the FA Cup, with Sheffield United progressing after winning 1-2 after extra time.
How to watch
This match kicks-off on Tuesday, November 22 at 20:00 GMT, and is live to watch on Sky Sports Arena.