Stoke City have fallen away from the chasing pack in recent weeks, and are now facing the prospect of a fifth straight season in the Championship unless things drastically change.
Michael O'Neill's side have won just one of their previous eight home league games.
They sit in 15th position in the Championship table and are 10 points from the play-off places.
The Tangerines have been inconsistent in recent weeks, with two draws, two losses and one win - a 4-1 thrashing of Reading last time out - in their previous five games.
They are 14th in the table and one point above Stoke having played an extra game, and so are nine points from the play-offs.
Key centre half Harry Souttar remains sidelined for the rest of the season.
Pool will be without right-back Jordan Gabriel for a number of weeks after he picked up a hamstring injury against Reading.
Sonny Carey (foot), Luke Garbutt (knee) and Grant Ward (achilles) all remain sidelined.
Stoke City (3-5-2)
Bursik; Wilmot, Harwood-Bellis, Jagielka; Smith, Baker, Allen, Powell, Tymon; Brown, Maja.
Grimshaw; Sterling, Ekpiteta, Thorniley, James; Bowler, Dougall, Stewart, Hamilton; Yates, Madine.
Ones to watch
23-year-old Maja is a name that will be familiar to many in English football after his starring role on the Netflix series 'Sunderland 'Til I Die' back in 2018-19. He was a Black Cats academy graduate and fired in 17 goals in 49 games in two seasons on Wearside before moving to Bordeaux in January 2019.
After failing to breakthrough in two years in France and a loan spell with Fulham last season, the Nigerian international joined Stoke on loan in January with an option to make the move permanent in the summer. He has netted two goals in six games so far and his strong hold-up and link-up play looks a good fit for the Potters' style.
Bowler has enjoyed a breakthrough season in 2021/22, after joining Blackpool from Everton on a free transfer in the summer. The 22-year-old winger failed to make an impression at Hull City in the 2019/20 season, scoring just one goal in 31 games.
He has looked at home in the second tier since joining Neil Critchley's side, and his good form saw him touted for a move to Nottingham Forest or Bournemouth in January. A very tricky customer for full-backs, Bowler has netted seven goals and picked up three assists in 37 games in this campaign. Stoke's defence will have to be on high alert with him around on Saturday.
The reverse fixture saw Stoke come out as 1-0 victors with a late goal from Steven Fletcher.
Stoke are looking to complete a league double over their opponents for the first time since the 1999/00 season.
The last meeting between the teams at the bet365 Stadium saw the Tangerines win 1-0 courtesy of a DJ Campbell goal in the Premier League.
Blackpool have won just two of the previous 13 games between the teams, with eight Stoke wins and three draws.
How to watch
The game kicks off at 15:00 GMT on Saturday March 5.
It is not available to watch in the UK but overseas supporters can purchase a live stream of the game via either club website.