Meanwhile, Mexico are currently bottom of the group, picking up just the one point against Poland, before being beaten by Argentina in the second round of the tournament.
However, both sides (especially Mexico), will be aware that victory will almost guarantee either side a place in the knockout stages.
The middle-eastern side have been hit with a major injury blow, as captain Salman Al Faraj has been ruled out for the remainder of the competition, with a shin injury.
Similarly, full-back Mohammed Al Burayk has a calf problem and remains an injury doubt, whilst Abdulelah Al Malki will miss the match, through suspension.
Therefore, the nation will be hoping their remaining squad, can step up and use the absentees as motivation to get a result and reach the World Cup knockout stages for the second time. It would be their first since the 1994 USA World Cup, until they were knocked out by Sweden.
As for their opponents, striker Raul Jimenez will be hoping to make his first ever World Cup start for his country, after a tough few months with injury. The Wolves forward has played just 90 minutes of football since August.
Tata Martino's side will most likely revert to a back four, meaning a holding midfielder could return. Therefore, it is very likely that midfielder Edson Alvarez will be recalled to the starting eleven.
However, Mexico could also be without their captain Andres Guardado, after he picked up a muscular injury during their match against Argentina.
Mohammed Al-Owais (GK) ; Saud Abdulhamid, Abdulelah Al-Amri, Ali Al-Boleahi, Sultan Al-Ghannam ; Abdulrahman Alobud ; Firas Al-Burakin, Sami Al-Najei, Mohamed Kanno, Salem Al-Dawsari ; Saleh Al-Shehri (4-1-4-1)
Salem Al-Dawsari (Saudi Arabia)
Winger Al-Dawsari has had mixed fortunes in the World Cup so far and will be keen to bounce back, when his country needs him the most.
He began the tournament with a sublime winning goal against Argentina, sealing what was, one of the biggest shocks in World Cup history.
Therefore, he will be desperate to put the miss behind him, and send his side through to the next round of the tournament.
Hirving Lozano (Mexico)
Mexico's standout player is Napoli's Lozano, who has consistently caught the eye for his nation at the tournament so far.
The 27-year-old is yet to contribute to a goal so far, but has created a handful of chances, and caused opposition defenders, some serious problems so far.
The nation are yet to score in Qatar, and will be going into their final group game, needing their key men to step up and deliver on the big stage.
Lozano has scored five goals, and assisted a further three in all competitions for club and country this season. He will be keen to add to that tally, knowing that the nation have to win, and hope results go their way.
Where will the match be played?
What time is kick-off?
Kick-off at the Lusail Iconic Stadium, will be at 7pm UK Time, which is in-line with Group C's other game between Poland and Argentina.
How can I watch the game?
The match will be shown live on the BBC for supporters in England, with the program beginning at 6:45pm on BBC Two. This is 15 minutes before kick-off. It will also be live on FOX for oversees viewers, in both Spanish and English.